US Dept of Labor

Occupational Safety & Health AdministrationWe Can Help

Hydrazine

General Description

  • Synonyms: Hydrazine, anhydrous
  • OSHA IMIS Code Number: 1390
  • Chemical Abstracts Service (CAS) Registry Number: 302-01-2
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: MU7175000
  • Department of Transportation Regulation Number (49 CFR 172.101) and Emergency Response Guidebook: 2029 132 (anhydrous); 3293 152 (=37% solution); 2030 153 (37-64% solution); 2029 132 (>64% solution)
  • NIOSH Pocket Guide to Chemical Hazards, Hydrazine: chemical description, physical properties, potentially hazardous incompatibilities, and more

Exposure Limits

  • OSHA Permissible Exposure Limit (PEL):
  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.01 ppm TWA; Skin; Appendix A3 (Confirmed Animal Carcinogen with Unknown Relevance to Humans)
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.03 ppm, 0.04 mg/m3 Ceiling (120 Minutes); Appendix A - Potential Occupational Carcinogen

Health Factors

  • Carcinogenic Classification:
  • NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 50 ppm
  • Potential Symptoms: Eye, nose, throat irritation; temporary blindness; dizziness; nausea; dermatitis; skin, eye burns; malar rash, photosensitivity, antinuclear antibody, antibody to nDNA (one case); coma (one case); (carcinogenic); In animals: bronchitis, pulmonary edema; liver, kidney damage; convulsions
  • Health Effects: Irritation-Respiratory tract-Marked (HE14); Cumulative organ damage (HE3); Mutagen (HE2)
  • Affected Organs: CNS, respiratory system, skin, eyes
  • Literature Basis:
    • U.S. Environmental Protection Agency, Technology Transfer Network Air Toxics Website, Hydrazine (coma and other symptoms).
    • Reidenberg, M.M., Durant, P.J., Harris, R.A., De Boccardo, G., Lahita, R. and Stenzel, K.H.: Lupus erythematosus-like disease due to hydrazine. Am. J. Med. 75: 365-370, 1983 (malar rash, photosensitivity, antinuclear antibody, antibody to nDNA).
  • Date Last Revised: 05/29/03

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • Two Coated Glass Fiber Filters (37 mm) in 3 piece cassette. Coating is Sulfuric Acid.
  • maximum volume: 240 Liters
  • maximum flow rate: 1.0 L/min
  • current analytical method: High Performance Liquid Chromatography; HPLC/UV
  • method reference: OSHA Manual of Analytical Methods (OSHA 108)
  • method classification: Fully Validated
  • note: The two filters are separated by the ring section of the 3 piece cassette, thereby, providing a backup portion to the sampling train.
On-Site Sampling Techniques/Methods:
  • Detector Tube
  • manufacturer: AUER/MSA
  • model/type: Hydrazine-0.5, AUER P/N 5086-832
  • sampling information: follow manufacturer's instructions
  • upper measurement limit: 3200 ppm
  • detection limit: approx. 20 ppm
  • overall uncertainty: unknown
  • method reference: on-site air secondary (manufacturer)
  • Detector Tube
  • manufacturer: Dräger
  • model/type: Hydrazine 0.2/a, order no. 67 33121
  • sampling information: 10 or 20 strokes
  • upper measurement limit: 10 ppm
  • detection limit: approx. 0.1 ppm
  • overall uncertainty: 25%
  • method reference: on-site air secondary (manufacturer)
  • Detector Tube
  • manufacturer: Dräger
  • model/type: Hydrazine 0.25/a, order no. CH 31801
  • sampling information: 10 or 20 strokes
  • upper measurement limit: 5 ppm
  • detection limit: approx. 0.05 ppm
  • overall uncertainty: 16%
  • method reference: on-site air secondary (manufacturer)
  • Detector Tube
  • manufacturer: Gastec
  • model/type: 185
  • sampling information: 5 or 10 strokes
  • upper measurement limit: 2.0 ppm
  • detection limit: 0.01 ppm
  • overall uncertainty: 16% for 0.1 to 0.5 ppm, 8% for 0.5 to 2 ppm
  • method reference: on-site air secondary (manufacturer)
  • device
  • manufacturer: Matheson-Kitagawa
  • model/type: 8014-219S
  • sampling information: follow manufacturer's instructions
  • upper measurement limit: 10 ppm
  • detection limit: approx. 0.1 ppm
  • overall uncertainty: unknown
  • method reference: on-site air secondary (manufacturer)
Bulk Method:
  • Limit the amount of bulk submitted to one gram or one mL.

** All Trademarks are the property of their respective owners.

Search Chemical Sampling Information

Index

By Name

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

By CAS Number
collage image - OSHA Salt Lake Technical Center

*Accessibility Assistance: Contact OSHA's Directorate of Technical Support and Emergency Management at (202) 693-2300 for assistance accessing PDF materials.

All other documents, that are not PDF materials or formatted for the web, are available as Microsoft Office® formats and videos and are noted accordingly. If additional assistance is needed with reading, reviewing or accessing these documents or any figures and illustrations, please also contact OSHA's Directorate of Technical Support and Emergency Management at (202) 693-2300.

**eBooks - EPUB is the most common format for e-Books. If you use a Sony Reader, a Nook, or an iPad you can download the EPUB file format. If you use a Kindle, you can download the MOBI file format.

Back to Top

Thank You for Visiting Our Website

You are exiting the Department of Labor's Web server.

The Department of Labor does not endorse, takes no responsibility for, and exercises no control over the linked organization or its views, or contents, nor does it vouch for the accuracy or accessibility of the information contained on the destination server. The Department of Labor also cannot authorize the use of copyrighted materials contained in linked Web sites. Users must request such authorization from the sponsor of the linked Web site. Thank you for visiting our site. Please click the button below to continue.

Close