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Chemical Sampling Information (CSI)
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General Description

Synonyms: 1,2-Dihydroxyethane; 1,2-Ethanediol; Glycol; Glycol alcohol; Monoethylene glycol

OSHA IMIS Code Number: 1911

Chemical Abstracts Service (CAS) Registry Number: 107-21-1

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: KW2975000

NIOSH Pocket Guide to Chemical Hazards, Ethylene Glycol: chemical description, physical properties, potentially hazardous incompatibilities, and more


Exposure Limits

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 100 mg/m3 Ceiling (Aerosol only); Appendix A4 - Not Classifiable as a Human Carcinogen

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): Appendix D - Substances With No Established RELs


Health Factors

Potential Symptoms: Irritation of eyes, skin, nose, throat; lassitude (weakness, exhaustion); headache, dizziness, central nervous system depression; abnormal eye movements (nystagmus); skin sensitization; INGES ACUTE: Abdominal pain, nausea, vomiting, loss of coordination, stupor, convulsions, unconsciousness; rapid heart rate, congestive heart failure; kidney damage, failure (delayed).

Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15) CNS depression (HE7)

Affected Organs: Eyes, skin, respiratory system, CNS

Notes: Exposure by ingestion can be determined by urinalysis for oxalic acid, a metabolite of ethylene glycol.

Date Last Revised: 06/04/2004

Literature Basis:
  • NIOSH Pocket Guide to Chemical Hazards: Ethylene Glycol.
  • International Chemical Safety Cards (WHO/IPCS/ILO): Ethylene Glycol.
  • EPA Air Toxics Website: Ethylene Glycol. U.S. Environmental Protection Agency Technology Transfer Network.
  • Pohanish, R.P. (editor): Ethylene Glycol. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1088-1090.
Monitoring Methods used by OSHA

Laboratory Sampling/Analytical Method:
  • sampling media: OSHA Versatile Sampler (OVS-7) - 13 mm XAD-7 tube (270/140 mg sections, 20/60 mesh) with a Glass Fiber Filter enclosed
    analytical solvent: Methanol
    maximum volume: 60 Liters
    maximum flow rate: 2 L/min
    current analytical method: Gas Chromatography; GC/FID
    method reference: NIOSH Analytical Method (NIOSH 5523) [36 KB PDF, 5 pages]
    method slassification: Partially Validated
    note: Ship cold to the laboratory for analysis.
On-Site Sampling Techniques/Methods:
  • device: Detector Tube
    manufacturer: Dräger
    model/type: Ethylene Glycol 10, order no. 81 01351
    sampling information: 10 strokes
    upper measurement limit: 180 mg/m3
    detection limit: approximately 5 mg/m3
    overall uncertainty: approximately 41%
    method reference: on-site air secondary (manufacturer)

  • device: Detector Tube
    manufacturer: Gastec
    model/type: 165L
    sampling information: 2 strokes
    upper measurement limit: 100 mg/m3
    detection limit: 2 mg/m3
    overall uncertainty: 25% for 10 to 50 mg/m3, 16% for 50 to 100 mg/m3
    method reference: on-site air secondary (manufacturer)
  • device: Detector Tube
    manufacturer: Matheson-Kitagawa
    model/type: 8014-232SB
    sampling information: 3 strokes
    upper measurement limit: 40 mg/m3
    detection limit: approximately 1 mg/m3
    overall uncertainty: unknown
    method reference: on-site air secondary (manufacturer)

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Page last updated: 11/12/2004

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