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Ethanolamine

General Description

Synonyms: 2-Aminoethanol; β-Aminoethyl alcohol; Ethylolamine; 2-Hydroxyethylamine; Monoethanolamine

OSHA IMIS code: 1030

CAS number: 141-43-5

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method:
  • coated XAD-2 tube (80/40 sections, 20/60 mesh); coating is 10% (w/w) 1-Naphthylisothiocyanate (NITC) 
  • maximum volume: 10 L
  • maximum flow rate: 0.1 L/min (TWA) 
  • maximum volume: 1.5 L
  • maximum flow rate: 0.1 L/min (STEL) 
  • current analytical method: high performance liquid chromatography; HPLC/UV 
  • analytical solvent: Dimethylformamide 
  • method reference: OSHA PV2111 (partially validated)

Exposure Limits and Health Effects (Updated September 6, 2012)

Standard Set By Exposure Limit Health Effect Codes -- Health Effects and Target Organs

OSHA PEL - General Industry
See 29 CFR 1910.1000 Table Z-1

3 ppm (6 mg/m3) TWA HE7 -- central nervous system stimulant (low doses)
HE8 -- central nervous system depressant (lethal doses)
HE16 -- mild skin and eye irritation
OSHA PEL - Construction Industry
See 29 CFR 1926.55 Appendix A
3 ppm (6 mg/m3) TWA HE7 -- central nervous system stimulant (low doses)
HE8 -- central nervous system depressant (lethal doses)
HE16 -- mild skin and eye irritation
OSHA PEL - Shipyard Employment
See 29 CFR 1915.1000 Table Z-Shipyards
3 ppm (6 mg/m3) TWA HE7 -- central nervous system stimulant (low doses)
HE8 -- central nervous system depressant (lethal doses)
HE16 -- mild skin and eye irritation
NIOSH REL 3 ppm (8 mg/m3) TWA
6 ppm (15 mg/m3) STEL
HE8 -- narcosis
HE16 -- skin, eye, and respiratory irritation
ACGIH TLV® (1985) 3 ppm (8 mg/m3) TWA
6 ppm (15 mg/m3) STEL
HE7 -- apathy and poor appetite
HE16 -- mild skin and eye irritation
CAL/OSHA PELs 3 ppm (8 mg/m3) TWA
6 ppm (15 mg/m3) STEL
HE7 -- apathy and poor appetite
HE16 -- mild skin and eye irritation

Carcinogenic classification:

  • NTP: Not listed
  • IARC: Not listed
  • EPA: Not listed

EPA Inhalation Reference Concentration (RfC): Not established

ATSDR Inhalation Minimal Risk Levels (MRLs): Not established

NIOSH IDLH concentration: 30 ppm

Notes on other potential health effects and hazards:

  1. Ethanolamine is combustible and gives off irritating or toxic fumes in a fire (NIOSH/IPCS 2002).
  2. Explosive vapor/air mixtures may form above 85°C (NIOSH/IPCS 2002).
  3. A few cases of allergic contact dermatitis from exposure to ethanolamine in metalworking fluids have been reported (Geier et al. 2004).
  4. Ethanolamine is also a suspected cause of at least one case of asthma and a fatal case of acute respiratory distress syndrome (Kamijo et al. 2004).

Partial reference list:

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Ethanolamine. 2016.
  • Geier, J., Lessmann, H., Schnuch, A. and Uter, W.: Contact sensitizations in metalworkers with occupational dermatitis exposed to water-based metalworking fluids: results of the research project "FaSt". Int. Arch. Occup. Environ. Health 77(8): 543-551, 2004.
  • Kamijo, Y., Soma, K., Inoue, A., Nagai, T. and Kurihara, K.: Acute respiratory distress syndrome following asthma-like symptoms from massive ingestion of a monoethanolamine-containing detergent. Vet. Hum. Toxicol. 46(2): 79-80, 2004.
  • NIOSH: Occupational Health Guideline for Ethanolamine. 1978.
  • NIOSH/CEC/IPCS: International Chemical Safety CardsEthanolamine. October 10, 2002.

Chemical Sampling Information

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