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Chemical Sampling Information (CSI)
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General Description

Synonyms: Phenytoin; Difhydan; Dihycon; Di-Hydan; Di-Lan; Dilabid; Dilantin; Ekko; 5,5-Diphenyl-2,4-Imidazolidinedione; Hydantol; Zentropil

OSHA IMIS Code Number: D905

Chemical Abstracts Service (CAS) Registry Number: 57-41-0

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: MU1050000

Chemical Description and Physical Properties:

powder
molecular weight: 252.26
molecular formula: C15H12N2O2
melting point: 295-298°C
Health Factors

Carcinogenic Classification:

International Agency for Research on Cancer (IARC): Group 2B, possibly carcinogenic to humans [5 MB PDF, 63 pages] (Phenytoin)

National Toxicology Program (NTP): Reasonably anticipated to be human carcinogens [140 KB PDF, 2 pages]
Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):

  • sampling media: Coated Glass Fiber Filters (37 mm) Coating is H2SO4
    analytical solvent: Methanol
    maximum volume: 100 Liters
    maximum flow rate: 1.0 L/min
    current analytical method: High Performance Liquid Chromatography; HPLC/U.
    method reference: 2 (OSHA In-House File)
    method classification: Partially Validated

Conditions: Column: C8 Mobile Phase: 50:50 Acetonitrile:Water Detector Wavelength: 242nm or 257nm Detection Limit: 13.6 ng/inj

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