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1-Chloro-4-trifluoromethylbenzene

General Description

Synonyms: Benzene, 1-chloro-4-(trifluoromethyl)-; p-Chlorobenzotrifluoride; (p-Chlorophenyl)trifluoromethane; p-(Trifluoromethyl)chlorobenzene; p-Trifluoromethylphenyl chloride, p-Chloro-alpha, alpha, alpha-trifluorotoluene

OSHA IMIS code: R249

CAS number(s): 98-56-6; 92709-16-5

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method:
  • charcoal tube (100/50 mg sections, 20/40 mesh)
  • maximum volume: 10 L
  • maximum flow rate: 0.2 L/min (TWA)
  • current analytical method: gas chromatography; GC/FID
  • analytical solvent: (99:1) carbon disulfide/methanol
  • method reference: NIOSH 1026 (partially validated)
  • note: Samples must be refrigerated for shipment to the laboratory. Sample stability is 7 days at 25°C; and 30 days at 5°C.

Exposure Limits and Health Effects (Updated September 6, 2012)

Standard Set By Exposure Limit Health Effect Codes -- Health Effects and Target Organs
OSHA PEL Not established
NIOSH REL Not established
ACGIH TLV® Not established
CAL/OSHA PELs Not established

Carcinogenic classification:

  • NTP: Not listed
  • IARC: Not listed
  • EPA: Not listed

EPA Inhalation Reference Concentration (RfC): Not established

ATSDR Inhalation Minimal Risk Levels (MRLs): Not established

NIOSH IDLH concentration: Not established

Notes on other potential health effects and hazards:

  1. Exposure may cause irritation to the skin, eyes, and mucous membranes (Pohanish 2008).
  2. In June 2009, the National Toxicology Program developed a Chemical Information Profile for 1-Chloro-4-(trifluoromethyl)benzene [CAS No. 98-56-6] supporting nomination for toxicological evaluation (NTP 2009).

Partial reference list:

Chemical Sampling Information

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