- Synonyms: Benzene, 1-chloro-4-(trifluoromethyl)-; p-Chlorobenzotrifluoride; (p-Chlorophenyl)trifluoromethane; p-(Trifluoromethyl)chlorobenzene; p-Trifluoromethylphenyl chloride, p-Chloro-alpha, alpha, alpha-trifluorotoluene
- OSHA IMIS Code Number: R249
- Chemical Abstracts Service (CAS) Registry Number: 98-56-6
- Other Chemical Abstracts Service (CAS) Registry Number: 92709-16-5
Exposure Limits and Health Effects
|Exposure Limit||Limit Values||HE Codes||Health Factors and Target Organs|
OSHA Permissible Exposure Limit (PEL)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL)
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV)
- National Toxicology Program (NTP) carcinogenic classification: Not listed
- International Agency for Research on Cancer (IARC) carcinogenic classification: Not listed
- U.S. Environmental Protection Agency (EPA) carcinogenic classification: Not listed
- EPA Inhalation Reference Concentration (RfC): Not established
- Agency for Toxic Substances and Disease Registry (ATSDR) Inhalation Minimal Risk Level (MRL): Not established
- NIOSH Immediately Dangerous to Life or Health (IDLH) concentration: Not established
- Notes on Other Potential Health Effects and Hazards
- Exposure may cause irritation to the skin, eyes, and mucous membranes (Pohanish 2008).
- In June 2009, the National Toxicology Program developed a Chemical Information Profile for 1-Chloro-4-(trifluoromethyl)benzene [CAS No. 98-56-6] supporting nomination for toxicological evaluation (NTP 2009).
- Date Last Revised: 9/6/2012
- Literature Basis:
- NTP: Chemical Information Profile for 1-Chloro-4-(trifluoromethyl)benzene (PDF). 2009.
- Pohanish, R.P.: Sittig’s Handbook of Toxic and Hazardous Chemical Carcinogens 5th Edition, Volume 1: A-H, Volume 2: I-Z. William Andrew, Norwich, NY, p. 603, 2008.
Monitoring Methods used by OSHA
Laboratory Sampling/Analytical Method:
- charcoal tube (100/50 mg sections, 20/40 mesh)
- analytical solvent: Carbon Disulfide/Methanol (99:1)
- maximum volume: 10 Liters
- maximum flow rate: 0.2 L/min (TWA)
- current analytical method: Gas Chromatography; GC/FID
- method reference: NIOSH Analytical Method (NIOSH 1026 (PDF))
- method classification: Partially Validated
note: Samples must be refrigerated for shipment to laboratory. Sample stability is 7 days at 25°C; and 30 days at 5°C.
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