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Synonyms: Trichloroisocyanuric acid; Sodium dichloroisocyanurate; Hypochlorites; N-chloro compounds; Calcium hypochlorite
OSHA IMIS Code Number: C110
Chemical Abstracts Service (CAS) Registry Number: 7782-50-5
Other Chemical Abstracts Service (CAS) Registry Numbers: 2893-78-9; 87-90-1; 7778-54-3
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: FO2100000
Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1017 124
NIOSH Pocket Guide to Chemical Hazards, Chlorine: chemical description, physical properties, potentially hazardous incompatibilities, and more
NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 10 ppm
Potential Symptoms: Eye, nose, mouth, skin burns; lacrimation; rhinorrhea; coughing, choking; nausea, vomiting; substernal pain; headache; dizziness, syncope; pulmonary edema; persistent airways obstruction, bronchial hyper-responsiveness; hypoxemia; dermatitis; CNS impairment (balance, reaction time, color confusion, visual field performance, blink latency, cognition, verbal recall, adverse mood states); decreased grip strength
Health Effects: Lung injury (HE11); Irritation-Eyes, Nose, Throat, Bronchi, Skin---Marked (HE14); Central Nervous System Disturbances (HE7)
Affected Organs: Respiratory system; CNS
- The persistent respiratory symptoms after acute exposure have been called "Reactive airways dysfunction syndrome" (RADS), and unlike occupational asthma, RADS appears to be less responsive to bronchodilator (albuterol) inhalation therapy.
- (persistent respiratory symptoms)
Bhérer, L., Cushman, R., Courteau, J.P., Quévillon, M., Côté, G., Bourbeau, J., L'Archevêque, J., Cartier, A. and Malo, J.L.: Survey of construction workers repeatedly exposed to chlorine over a three to six month period in a pulpmill. II. Follow up of affected workers by questionnaire, spirometry, and assessment of bronchial responsiveness 18 to 24 months after exposure ended. Occup. Environ. Med. 51(4): 225-228, 1994.
- (resistance to albuterol)
Gautrin, D., Boulet, L.P., Boutet, M., Dugas, M., Bhérer, L., L'Archevêque, J., Laviolette, M., Côté, G. and Malo, J.L.: Is reactive airways dysfunction syndrome a variant of occupational asthma? J. Allergy Clin. Immunol. 93(1 Pt. 1): 12-22, 1994.
- (CNS impairment)
Kilburn, K.H.: Chlorine-induced damage documented by neurophysiological, neuropsychological, and pulmonary testing. Arch. Environ. Health 55(1): 31-37, 2000.
Date Last Revised: 05/13/2003
Primary Laboratory Sampling/Analytical Method (SLC1):
- sampling media: PTFE Membrane, 25-mm, 0.5 um pore with porous plastic support pad in a carbon-filled cassette SKC catalog nos. 225-1798, 225-2901, 225-3-23 or equivalent. Do not use cowl
maximum volume: 480 Liters
maximum flow rate: 2.0 L/min
current analytical method: Ion Specific Electrode; ISE
method reference: OSHA Manual of Analytical Methods (OSHA ID-101)
method classification: Partially Validated
note: Submit as separate sample. If Chlorine also expected, use a PTFE membrane/polypropylene cassette, followed by a Midget Fritted Glass Bubbler (MFGB) containing 15 mL 0.1% Sulfamic Acid for Chlorine Collection. Sample analyzed for equivalent chlorine levels. After sampling transfer membrane to separate vial containing 5 mL 0.1% Sulfamic acid. Seal and ship to the Salt Lake Technical Center.
Wipe Sampling Method:
- sampling media: Glass Fiber filter
0.1% Sulfamic acid
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