UNITED STATES
DEPARTMENT OF LABOR

• OSHA IMIS Code Number: 0640
• Chemical Abstracts Service (CAS) Registry Number: 7782-50-5
• NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: FO2100000
• Department of Transportation Regulation Number (49 CFR 172.101) and Emergency Response Guidebook: 1017 124
• NIOSH Pocket Guide to Chemical Hazards, Chlorine: chemical description, physical properties, potentially hazardous incompatibilities, and more

• OSHA Permissible Exposure Limit (PEL):
  • General Industry: 29 CFR 1910.1000 Z-1 Table -- 1 ppm, 3 mg/m³ Ceiling
  • Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 1 ppm, 3 mg/m³ TWA
• American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.5 ppm, 1.5 mg/m³ TWA; 1 ppm, 2.9 mg/m³ STEL; Appendix A4 (Not Classifiable as a Human Carcinogen)
• National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.5 ppm TWA; 1 ppm STEL

• NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 10 ppm
• Potential Symptoms: Eye, nose, mouth, skin burns; lacrimation; rhinorrhea; coughing, choking; nausea, vomiting; substernal pain; headache; dizziness, syncope; pulmonary edema; persistent airways obstruction, bronchial hyper-responsiveness; hypoxemia; dermatitis; CNS impairment (balance, reaction time, color confusion, visual field performance, blink latency, cognition, verbal recall, adverse mood states); decreased grip strength
• Health Effects: Lung injury (HE11); Irritation-Eyes, Nose, Throat, Bronchi, Skin---Marked (HE14); Central Nervous System Disturbances (HE7)
• Affected Organs: Respiratory system; CNS
• Notes:
1. The persistent respiratory symptoms after acute exposure have been called "Reactive airways dysfunction syndrome" (RADS), and unlike occupational asthma, RADS appears to be less responsive to bronchodilator (albuterol) inhalation therapy.
• Literature Basis:
• (persistent respiratory symptoms)
  Bhérer, L., Cushman, R., Courteau, J.P., Quévillon, M., Côté, G., Bourbeau, J., L'Archevéque, J., Cartier, A. and Malo, J.L.: Survey of construction workers repeatedly exposed to chlorine over a three to six month period in a pulpmill. II. Follow up of affected workers by questionnaire, spirometry, and assessment of bronchial responsiveness 18 to 24 months after exposure ended. Occup. Environ. Med. 51(4): 225-228, 1994.
• (resistance to albuterol)
  Gautrin, D., Boulet, L.P., Boutet, M., Dugas, M., Bhérer, L., L'Archevéque, J., Laviolette, M., Côté, G. and Malo, J.L.: Is reactive airways dysfunction syndrome a variant of occupational asthma? J. Allergy Clin. Immunol. 93(1 Pt. 1): 12-22, 1994.
• (CNS impairment)
  Kilburn, K.H.: Chlorine-induced damage documented by neurophysiological, neuropsychological, and pulmonary testing. Arch. Environ. Health 55(1): 31-37, 2000.
• Date Last Revised: 05/13/2003

Primary Laboratory Sampling/Analytical Method (SLC1):

On-Site Sampling Techniques/Methods: