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Chemical Sampling Information (CSI)
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General Description

Synonyms: 2-Camphonone; Synthetic camphor; Gum camphor; Laurel camphor

OSHA IMIS Code Number: 0522

Chemical Abstracts Service (CAS) Registry Number: 76-22-2

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: EX1225000

Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 2717 133

NIOSH Pocket Guide to Chemical Hazards, Camphor (Synthetic): chemical description, physical properties, potentially hazardous incompatibilities, and more

Exposure Limits

OSHA Permissible Exposure Limit (PEL):

General Industry: 29 CFR 1910.1000 Z-1 Table -- 2 mg/m3 TWA (PEL listed as Camphor, Synthetic)

Construction Industry: 29 CFR 1926.55 Appendix A -- 2 mg/m3 TWA (PEL listed as Camphor, Synthetic)

Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 2 mg/m3 TWA (PEL listed as Camphor, Synthetic)

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 2 ppm, 12 mg/m3 TWA; 3 ppm, 19 mg/m3 STEL; Appendix A4 - Not Classifiable as a Human Carcinogen (TLV listed as Camphor, Synthetic)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 2 mg/m3 TWA (REL listed as Camphor (Synthetic))

Health Factors

NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 200 mg/m3

Potential Symptoms: Irritation of eyes, skin, mucous membrane; nausea, vomiting, diarrhea; headache, dizziness, excitement, epileptiform convulsions; cough, sore throat; INGES ACUTE: Burning sensation in throat and chest; GI symptoms; confusion, seizures, unconsciousness; SKIN ABS: Hepatotoxicity without GI symptoms.

Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15) Acute Toxicity---short-term high hazard effects (HE4) CNS Effects (HE7)

Affected Organs: Eyes, skin, respiratory system, CNS

Notes:

  1. Most reported intoxications with camphor involve children under the age of 6 years. No occupational poisoning reports were found in the literature over the past 30 years.
  2. A reversible elevation of liver enzymes in an infant from absorption of camphor in Vicks VapoRub through the skin has been reported.
  3. Chronic ingestion may produce symptoms mimicking Reye's Syndrome.
  4. d-Camphor is listed among FDA's "food additives permitted for direct addition to food for human consumption" (21 CFR 172.515)

Literature Basis:

  • NIOSH Pocket Guide to Chemical Hazards: Camphor (Synthetic).
  • International Chemical Safety Cards (WHO/IPCS/ILO): Camphor.
  • Mallinckrodt Baker, Inc.: Material Safety Data Sheet. DL-Camphor.
  • Pohanish, R.P. (editor): Camphor. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 475-476.
  • Uc, A., Bishop, W.P. and Sanders, K.D.: Camphor hepatotoxicity. South. Med. J. 93(6): 596-598, 2000.

Date Last Revised: 05/18/2004

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):

  • sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
    analytical solvent: (99:1) Carbon Disulfide:Methanol
    maximum volume: 24 Liters
    maximum flow rate: 0.2 L/min
    current analytical method: Gas Chromatography; GC/FID
    method reference: NIOSH Analytical Method (NIOSH 1301 [25 KB PDF, 5 pages])
    method classification: Partially Validated

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