Synonyms: 2-Camphonone; Synthetic camphor; Gum camphor; Laurel camphor
OSHA IMIS Code Number: 0522
Chemical Abstracts Service (CAS) Registry Number: 76-22-2
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: EX1225000
Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 2717 133
NIOSH Pocket Guide to Chemical Hazards, Camphor (Synthetic): chemical description, physical properties, potentially hazardous incompatibilities, and more
OSHA Permissible Exposure Limit (PEL):
General Industry: 29 CFR 1910.1000 Z-1 Table -- 2 mg/m3 TWA (PEL listed as Camphor, Synthetic)
Construction Industry: 29 CFR 1926.55 Appendix A -- 2 mg/m3 TWA (PEL listed as Camphor, Synthetic)
29 CFR 1915.1000 Table Z-Shipyards -- 2 mg/m3 TWA (PEL listed as Camphor, Synthetic)
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 2 ppm, 12 mg/m3 TWA; 3 ppm, 19 mg/m3 STEL; Appendix A4 - Not Classifiable as a Human Carcinogen (TLV listed as Camphor, Synthetic)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 2 mg/m3 TWA (REL listed as Camphor (Synthetic))
NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 200 mg/m3
Potential Symptoms: Irritation of eyes, skin, mucous membrane; nausea, vomiting, diarrhea; headache, dizziness, excitement, epileptiform convulsions; cough, sore throat; INGES ACUTE: Burning sensation in throat and chest; GI symptoms; confusion, seizures, unconsciousness; SKIN ABS: Hepatotoxicity without GI symptoms.
Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15) Acute Toxicity---short-term high hazard effects (HE4) CNS Effects (HE7)
Affected Organs: Eyes, skin, respiratory system, CNS
- Most reported intoxications with camphor involve children under the age of 6 years. No occupational poisoning reports were found in the literature over the past 30 years.
- A reversible elevation of liver enzymes in an infant from absorption of camphor in Vicks VapoRub through the skin has been reported.
- Chronic ingestion may produce symptoms mimicking Reye's Syndrome.
- d-Camphor is listed among FDA's "food additives permitted for direct addition to food for human consumption" (21 CFR 172.515)
- NIOSH Pocket Guide to Chemical Hazards: Camphor (Synthetic).
- International Chemical Safety Cards (WHO/IPCS/ILO): Camphor.
- Mallinckrodt Baker, Inc.: Material Safety Data Sheet. DL-Camphor.
- Pohanish, R.P. (editor): Camphor. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 475-476.
- Uc, A., Bishop, W.P. and Sanders, K.D.: Camphor hepatotoxicity. South. Med. J. 93(6): 596-598, 2000.
Date Last Revised: 05/18/2004
Primary Laboratory Sampling/Analytical Method (SLC1):
- sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
analytical solvent: (99:1) Carbon Disulfide:Methanol
maximum volume: 24 Liters
maximum flow rate: 0.2 L/min
current analytical method: Gas Chromatography; GC/FID
method reference: NIOSH Analytical Method (NIOSH 1301 [25 KB PDF, 5 pages])
method classification: Partially Validated
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