Chemical Hazards and Toxic Substances

Additional Resources

General Chemical Information
  • OSHA Occupational Chemical Database. OSHA's premier one-stop shop for occupational chemical information. It compiles information from several government agencies and organizations. Information available on the pages includes chemical identification and physical properties, exposure limits, sampling information, and additional resources.
  • Occupational Health Guidelines for Chemical Hazards. U.S. Department of Health and Human Services (DHHS), National Institute for Occupational Safety and Health (NIOSH) Publication No. 81-123, (January 1981). Provides a table of contents of guidelines for many hazardous chemicals. The files provide technical chemical information, including chemical and physical properties, health effects, exposure limits, and recommendations for medical monitoring, personal protective equipment (PPE), and control procedures.
  • International Programme on Chemical Safety. World Health Organization (WHO). The two main roles of the IPCS are to establish the scientific health and environmental risk assessment basis for safe use of chemicals and to strengthen national capabilities for chemical safety.
  • Integrated Risk Information System (IRIS). Environmental Protection Agency (EPA). The IRIS is a database of human health effects that may result from exposure to various substances found in the environment. The information in IRIS is intended for those without extensive training in toxicology, but with some knowledge of health sciences.
  • Health Effects Notebook for Hazardous Air Pollutants. Environmental Protection Agency (EPA). Provides a collection of documents that contain health effects information related to each of the EPA Hazardous Air Pollutants (HAPs) from the 1990 Clean Air Act Amendments.
  • Chemical Reactivity Worksheet. National Oceanic and Atmospheric Administration (NOAA), Office of Response and Restoration (OR&R). Provides a free program that can be used to research the reactivity of substances or mixtures of substances.
  • EXTOXNET - The EXTension TOXicology NETwork. The University of California-Davis, Oregon State University, Michigan State University, Cornell University, and the University of Idaho. Provides information more widely available via Pesticide Information Profiles, Toxicology Information Briefs, and Fact Sheets.
  • Where to find Material Safety Data Sheets on the Internet. Interactive Learning Paradigms Incorporated (ILPI). Provides links to MSDS available on the Internet.
  • For additional information on chemical reactivity, see OSHA's Chemical Reactivity Hazards Safety and Health Topics Page. Provides links to references that aid in evaluating chemical reactive interactions and their potential hazards.


  • Small Business Handbook. OSHA Publication 2209, (2005). Helps small business employers meet the legal requirements imposed by the Occupational Safety and Health Act of 1970 (the Act), and achieve an in-compliance status before an OSHA inspection.
  • Chemical Hazard Communication. OSHA Publication 3084, (Revised 1998). Establishes uniform requirements to ensure that the hazards of all chemicals imported into, produced, or used in US workplaces are evaluated, and that this hazard information is transmitted to affected employers and exposed employees.
  • Training Requirements in OSHA Standards. OSHA Publication 2254, (2015).
  • Draft Model Training Program for Hazard Communication. OSHA. Presents an approach to providing training using a series of lesson plans, slides, and quizzes that are provided in appendices which also include a glossary of commonly used terms and references.
  • Hazard Communication. OSHA. Assists trainers conducting OSHA 10-hour General Industry outreach training for workers. Since workers are the target audience, the material emphasizes hazard identification, avoidance, and control — not standards. No attempt has been made to treat the topic exhaustively.
  • Hazard Communication: Small Entity Compliance Guide for Employers That Use Hazardous Chemicals. OSHA Publication 3695, (2014).

Other Resources