Abstract: At 9:30 a.m. on November 8, 2015, an employee was cleaning inner lining of a railcar that was previously transporting latex. The employee lost consciousness while inside of railcar with oxygen-deficient atmosphere. First responders attempted to rescue employee but were unable to revive/resuscitate. A second employee who entered railcar, lost consciousness, was rescued, and transported to the local hospital for treatment. A third employee fell from the ladder inside of the railcar to the bottom of the car, lost consciousness, was able to conduct a self-rescue, and was transported to the local hospital for treatment.