OSHA's Controlling Occupational Exposure to Hazardous Drugs document describes the effective use of PPE such as gloves and gowns when working with hazardous drugs (Section V, C, #3).
- OSHA's Personal Protective Equipment (PPE) standard [29 CFR 1910.132] requires employers to provide appropriate PPE (e.g., gloves, goggles, splash aprons) for workers who may handle or be otherwise exposed to hazardous drugs.
- For more information see OSHA's Safety and Health Topics page - Personal Protective Equipment.
- Select appropriate gloves based on intended use for specific drug types (NIOSH).
- Wear two pairs of gloves when compounding, administering, and disposing of hazardous drugs.
- When double gloving, place one glove under the gown cuff and one over. The glove-gown interface should be such that no skin on the arm or wrist is exposed.
- To limit transfer of contamination from a C-PEC into the work area, remove the outer gloves after each task or batch, and place the outer gloves in "zipper" - closure plastic bags or other sealable containers for disposal.
- Change gloves regularly (e.g., hourly or more often, depending on the exposure), or immediately if they are torn, punctured, or contaminated from a spill.
- Wear a protective disposable gown made of lint-free, low-permeability fabric, with a solid front, long sleeves and tight-fitting elastic or knit cuffs.
- Hand-washing: Wash hands before gloves are put on and after they are removed.
- Restricted preparation areas: Perform hazardous drug preparation in a restricted area, with signs restricting the access of unauthorized personnel prominently displayed. [Controlling Occupational Exposure to Hazardous Drugs (Section V, B, #1)]
- Restricted activities: Do not smoke, drink, apply cosmetics, or eat where hazardous drugs are prepared, stored, or used, as these activities increase the chance of exposure. [Controlling Occupational Exposure to Hazardous Drugs (Section IV, A, #4)]