P-NITROPHENOL

Chemical Identification
Chemical Identification
CAS # 100-02-7
Formula

C₆H₅NO₃

Synonyms

4-hydroxynitrobenzene; 4-nitrophenol

Physical Properties
Physical Properties
Physical description A white to light yellow crystalline solid.
Boiling point 534°F Molecular weight 139.11
Freezing point/melting point 235-239°F (sublimes) Vapor pressure 1 mmHg
Flash point 377°F Vapor density 1.244 at 149°F
Specific gravity 1.48 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 3 NFPA fire rating 1
NFPA reactivity rating 2 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.)
Sampling group
Sampler/Sampling media
Sampling time*
Sampling volume (TWA)*
Sampling flow rate (TWA)*
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments
Method reference
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA TLV-TWA PEL-TWA
PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

NA

Skin notation

NA

Skin notation

NA

Skin notation

NA

Notes:

Not established

Notes:

Not established

Notes:

Not established

Notes:

Not established

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - 4-Nitrophenol

NIOSH: Pocket Guide to Chemical Hazards - 4-Nitrophenol

Literature References

  • EPA Air Toxics Website: 4-Nitrophenol. US Environmental Protection Agency Technology Transfer Network.
  • Barr, D.B., et al.: Measurement of p-nitrophenol in the urine of residents whose homes were contaminated with methyl parathion. Environ. Health Perspect. 110(Suppl. 6): 1085-1091, 2002.
  • Pohanish, R.P. (editor): Nitrophenols. Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1722-1725.
  • Qiao, G.L., Chang, S.K., Brooks, J.D. and Riviere, J.E.: Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration. Toxicol. Sci. 54(2): 284-294, 2000.

Last Updated Date : 01/08/2021