1. OSHA Occupational Chemical Database
  2. ALACHLOR
Label abbreviations descriptions

ALACHLOR

Chemical Identification
Chemical Identification
CAS # 15972-60-8
Formula

C₁₄H₂₀ClNO₂
Synonyms

lasso; acetanilide, 2 - chloro-2',6'-diethyl-N-(methoxymethyl); 2-chloro-N-(2,6-diethylphenyl) N-(methoxymethyl) acetamide; Alamex; alochlor; CP50144; metachlor; methachlor
Physical Properties
Physical Properties
Physical description Crystalline cream-colored solid.
Boiling point 212°F at 0.02 mmHg Molecular weight 269.77
Freezing point/melting point 104-106°F Vapor pressure 2.2x10-5 mmHg
Flash point 278.6°F (closed cup) Vapor density 9.3
Specific gravity 1.133 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1580
Sampling group
Sampler/Sampling media GFF with backup pad (BUP)
Sampling time*
Sampling volume (TWA)*

100 L
Sampling flow rate (TWA)*

1 L/min
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments HPLC
Method reference OSHA PV2035 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA TLV-TWA

1 mg/m³ (inhalable fraction and vapor) [2006]

 PEL-TWA
PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

NA

 Skin notation

NA

 Skin notation

NA

 Skin notation

NA
Notes:

Not established

 Notes:

Not established

 Notes:

dermal sensitization (DSEN)

 Notes:

Not established
Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: TLV-A3 Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Alachlor

NIOSH: Pocket Guide to Chemical Hazards - Alachlor

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Alachlor. See annual publication for most recent information.
  • EPA Consumer Ground Water & Drinking Water Factsheet on: Alachlor.
  • Acquavella, J.F., Delzell, E., Cheng, H., Lynch, C.F. and Johnson, G.: Mortality and cancer incidence among alachlor manufacturing workers. Occup. Environ. Med. 61(8): 680-685, 2004.
  • Coleman, S., Liu, S., Linderman, R. Hodgson, E. and Rose, R.L.: In vitro metabolism of alachlor by human liver microsomes and human cytochrome P450 isoforms. Chem. Biol. Interact. 122(1): 27-39, 1999.
  • Dearfield, K.L., McCarroll, N.E., Protzel, A., Stack, H.F., Jackson, M.A. and Waters, M.D.: A survey of EPA/OPP and open literature on selected pesticide chemicals. II. Mutagenicity and carcinogenicity of selected chloroacetanilides and related compounds. Mutat. Res. 443(1-2): 183-221, 1999.
  • Lee, W.J.: Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health Study. Am. J. Epidemiol. 159(4): 373-380, 2004.
  • Leet, T. et al.: Cancer incidence among alachlor manufacturing workers. Am. J. Ind. Med. 30(3): 300-306, 1996.
  • Sanderson, W.T., Biagini, R., Tolos, W., Henningsen, G. and MacKenzie, B.: Biological monitoring of commercial pesticide applicators for urine metabolites of the herbicide alachlor. Am. Ind. Hyg. Assoc. J. 56(9): 883-889, 1995.
  • Swan, S.H. et al.: Semen quality in relation to biomarkers of pesticide exposure. Environ. Health Perspect. 111(12): 1478-1484, 2003.
  • Won, J.H., Ahn, S.K. and Kim, S.C.: Allergic contact dermatitis from the herbicide Alachlor®. Contact Dermatitis 28(1): 38-39, 1993.

Last Updated Date : 12/15/2020