Lapse in Appropriations
For workplace safety and health, please call 800-321-6742; for mine safety and health, please call 800-746-1553; for Job Corps, please call 800-733-5627 and for Wage and Hour, please call 866-487-9243 (866-4-US-WAGE). This website is currently not being updated due to the suspension of Federal government services. The last update to the site was 10/1/2025. Updates to the site will start again when the Federal government resumes operations.
ACETOPHENONE
| CAS # | 98-86-2 |
|---|---|
| Formula |
C₈H₈O |
| Synonyms |
α-acetophenone; acetylbenzene; 1-phenylethanone; phenyl methyl ketone |
| Physical description | A colorless liquid with a sweet pungent taste and odor resembling the odor of oranges. | ||
|---|---|---|---|
| Boiling point | 395.1°F | Molecular weight | 120.16 |
| Freezing point/melting point | 67.5°F | Vapor pressure | |
| Flash point | 180°F | Vapor density | |
| Specific gravity | 1.028 | Ionization potential | |
| Lower explosive limit (LEL) | 1.1% | Upper explosive limit (UEL) | 6.7% |
| NFPA health rating | 2 | NFPA fire rating | 2 |
| NFPA reactivity rating | 0 | NFPA special instruction | |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | A169 |
|---|---|
| Sampling group | |
| Sampler/Sampling media | Tenax® GC tube (30/15 mg) [SKC 226-35] |
| Sampling time* | 120 min |
| Sampling volume (TWA)* | 12 L |
| Sampling flow rate (TWA)* | 0.1 L/min |
| Sampling volume (STEL/Peak/C)* | |
| Sampling flow rate (STEL/Peak/C)* | |
| Analytical method instruments | GC-FID |
| Method reference | OSHA PV2003 (partially validated) |
| Notes | |
| Special requirements |
* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media | |
|---|---|
| Bulk Method |
| Device | |||||
|---|---|---|---|---|---|
| Model/Type | |||||
|
Sampling information (see manufacturer instructions) |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
|||||
|---|---|---|---|---|---|---|---|
| PEL-TWA | REL-TWA | TLV-TWA | PEL-TWA |
10 ppm (49 mg/m³) |
|||
| PEL-STEL | REL-STEL | TLV-STEL | PEL-STEL | ||||
| PEL-C | REL-C | TLV-C | PEL-C | ||||
| Skin notation |
NA |
Skin notation |
NA |
Skin notation |
N |
Skin notation |
N |
|
Notes:
Not established |
Notes:
Not established |
Notes:
Visit the ACGIH TLV site for specific data |
Notes: | ||||
| Health factors: See NIH-NLM PubChem. | IDLH | ||||||
| Carcinogenic classifications: EPA-D | Notes: | ||||||
| AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3: | |||||||
Additional Resources and Literature References
|
NOAA: CAMEO Chemicals - Acetophenone NIOSH: Pocket Guide to Chemical Hazards - Acetophenone Literature References
|
Last Updated Date : 07/15/2025