ETHYLENE THIOUREA

Chemical Identification
Chemical Identification
CAS # 96-45-7
Formula

C₃H₆N₂S

Synonyms

1,3-ethylene-2-thiourea; N,N-ethylenethiourea; ETU; 2-imidazolidine-2-thione; 2-mercaptoimidazoline; 2-imidazolidinethione

Physical Properties
Physical Properties
Physical description White to pale-green, crystalline solid with a faint, amine odor.
Boiling point 446-595°F Molecular weight 102.2
Freezing point/melting point 392°F Vapor pressure 16 mmHg
Flash point 486°F Vapor density
Specific gravity Ionization potential 8.15 eV
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 2 NFPA fire rating 2
NFPA reactivity rating 1 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1159
Sampling group
Sampler/Sampling media Four-piece sampling cassette containing GFFs (37 mm) in series [SKC 225-724]
Sampling time*

240 min

Sampling volume (TWA)*

480 L

Sampling flow rate (TWA)*

2 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments HPLC
Method reference OSHA 95 (fully validated)
Notes
 

Sample open-faced!!

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

 

TLV-TWA
 

 

PEL-TWA
 

 

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

NA

Skin notation
 

N

Skin notation
 

NA

Skin notation
 

NA

Notes:
 

Not established

Notes:
 

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A. Use encapsulated form.

Notes:
 

Not established

Notes:
 

Not established

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: IARC-3, NIOSH-Ca, NTP-R Notes:
 

Ca

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Ethylene thiourea

NIOSH: Pocket Guide to Chemical Hazards - Ethylene thiourea

Literature References

 
  • EPA Air Toxics Website: Ethylene Thiourea. U.S. Environmental Protection Agency Technology Transfer Network.
  • No Author: Ethylene Thiourea. Report on Carcinogens (latest edition); U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
  • El Balkhi, S., Sandouk, P. and Galliot-Guilley, M.: Determination of ethylene thiourea in urine by HPLC-DAD. J. Anal. Toxicol. 29(4): 229-233, 2005.
  • Frakes, R.A.: Drinking water guideline for ethylene thiourea, a metabolite of ethylene bisdithiocarbamate fungicides. Regul. Toxicol. Pharmacol. 8(2): 207-218, 1988.
  • Huff, J.: IARC monographs, industry influence, and upgrading, downgrading, and under-grading chemicals: a personal point of view. International Agency for Research on Cancer. Int. J. Occup. Environ. Health 8(3): 249-270, 2002.
  • Pohanish, R.P. (editor): Ethylene Thiourea. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1102-1104.
  • Smith, D.M.: Ethylene thiourea: thyroid function in two groups of exposed workers. Br. J. Ind. Med. 41(3): 362-366, 1984.

Last Updated Date : 12/28/2020