ETHYLENE THIOUREA

Chemical Identification
CAS #	96-45-7
Formula	C₃H₆N₂S
Synonyms	1,3-ethylene-2-thiourea; N,N-ethylenethiourea; ETU; 2-imidazolidine-2-thione; 2-mercaptoimidazoline; 2-imidazolidinethione

Physical Properties
Physical description	White to pale-green, crystalline solid with a faint, amine odor.
Boiling point	446-595°F	Molecular weight	102.2
Freezing point/melting point	392°F	Vapor pressure	16 mmHg
Flash point	486°F	Vapor density
Specific gravity		Ionization potential	8.15 eV
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	2	NFPA fire rating	2
NFPA reactivity rating	1	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	1159
Sampling group
Sampler/Sampling media	Four-piece sampling cassette containing GFFs (37 mm) in series [SKC 225-724]
Sampling time^*	240 min
Sampling volume (TWA)^*	480 L
Sampling flow rate (TWA)^*	2 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	HPLC
Method reference	OSHA 95 (fully validated)
Notes	Sample open-faced!!
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA		TLV-TWA		PEL-TWA
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	N	Skin notation	NA	Skin notation	NA
Notes: Not established		Notes: CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A. Use encapsulated form.		Notes: Not established		Notes: Not established
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: IARC-3, NIOSH-Ca, NTP-R		Notes: Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Ethylene thiourea

NIOSH: Pocket Guide to Chemical Hazards - Ethylene thiourea

Literature References

EPA Air Toxics Website: Ethylene Thiourea. U.S. Environmental Protection Agency Technology Transfer Network.
No Author: Ethylene Thiourea. Report on Carcinogens (latest edition); U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
El Balkhi, S., Sandouk, P. and Galliot-Guilley, M.: Determination of ethylene thiourea in urine by HPLC-DAD. J. Anal. Toxicol. 29(4): 229-233, 2005.
Frakes, R.A.: Drinking water guideline for ethylene thiourea, a metabolite of ethylene bisdithiocarbamate fungicides. Regul. Toxicol. Pharmacol. 8(2): 207-218, 1988.
Huff, J.: IARC monographs, industry influence, and upgrading, downgrading, and under-grading chemicals: a personal point of view. International Agency for Research on Cancer. Int. J. Occup. Environ. Health 8(3): 249-270, 2002.
Pohanish, R.P. (editor): Ethylene Thiourea. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1102-1104.
Smith, D.M.: Ethylene thiourea: thyroid function in two groups of exposed workers. Br. J. Ind. Med. 41(3): 362-366, 1984.

Last Updated Date : 12/28/2020

ETHYLENE THIOUREA

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References