DIPHENYL (BIPHENYL)‡

Chemical Identification
Chemical Identification
CAS # 92-52-4
Formula

C₁₂H₁₀

Synonyms

biphenyl; phenylbenzene; lemonene; xenene; 1,1-biphenyl; bibenzene

Physical Properties
Physical Properties
Physical description Colorless to pale-yellow solid with a pleasant, characteristic odor.
Boiling point 489°F Molecular weight 154.2
Freezing point/melting point 156°F Vapor pressure 0.005 mmHg
Flash point 235°F Vapor density 5.31
Specific gravity 1.04 Ionization potential 7.95 eV
Lower explosive limit (LEL) 0.6% at 232°F Upper explosive limit (UEL) 5.8% at 331°F
NFPA health rating 1 NFPA fire rating 1
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1011
Sampling group
Sampler/Sampling media XAD-7 tube (100/50 mg) [SKC 226-95]
Sampling time*

100 min

Sampling volume (TWA)*

20 L

Sampling flow rate (TWA)*

0.2 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA PV2022 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

0.2 ppm (1 mg/m³)

REL-TWA

0.2 ppm (1 mg/m³)

TLV-TWA

0.2 ppm [1979]

PEL-TWA

0.2 ppm (1.5 mg/m³)

PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1003, 13 Carcinogens.

Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

100 mg/m³

Carcinogenic classifications: EPA-D Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Biphenyl

NIOSH: Pocket Guide to Chemical Hazards - Diphenyl

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Biphenyl. See annual publication for most recent information.
  • U.S. EPA Integrated Risk Information System: 1,1-Biphenyl (CASRN 92-52-4).
  • Häkkinen, I., Siltanen, E., Hernberg, S., Seppäläinen, A.M., Karli, P. and Vikkula, E.: Diphenyl poisoning in fruit paper production: a new health hazard. Arch. Environ. Health 26(2): 70-74, 1973.
  • Halpaap, K., Horning, M.G. and Horning, E.C.: Metabolism of biphenyl in the rat. J. Chromatogr. 166(2): 479-490, 1978.
  • Meyer, T. and Scheline, R.R.: The metabolism of biphenyl. II. Phenolic metabolites in the rat. Acta Pharmacol. Toxicol. (Copenh.) 39(4): 419-432, 1976.
  • Pohanish, R.P. (editor): Biphenyl. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 341-342.
  • Tanaka, A., Morimoto, K. and Yamaha, T.: Small scale synthesis of labeled diphenyl and its binding to mouse liver microsomes. Radioisotopes 42: 564-568, 1993.
  • Wastensson, G., Hagberg, S., Andersson, E, Johnels, B. and Barregård, L.: Parkinson's disease in diphenyl-exposed workers-a causal association? Parkinsonism Relat. Disord. 12(1): 29-34, 2006.

Last Updated Date : 12/28/2020