Label abbreviations descriptions

2,6-TOLUENE-DIISOCYANATE (TDI)

Chemical Identification
CAS # 91-08-7
Formula
 

C₉H₆N₂O₂
Synonyms
 

2,6-toluene diisocyanate; 2,6-TDI; 2,6-diisocyanato-1-methylbenzene; 2,6-diisocyanatotoluene

Physical Properties
Physical description Colorless to pale-yellow solid or liquid with a pungent odor.
Boiling point 264-271°F Molecular weight 174.2
Freezing point/melting point 68-72°F Vapor pressure 0.5 mmHg at 77°F for 80% 2,4:20%; 2,6 TDI mixture
Flash point Vapor density 6
Specific gravity 1.2244 at 68°F Ionization potential
Lower explosive limit (LEL) 0.9% Upper explosive limit (UEL) 9.5%
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.) T177
Sampling group
Sampler/Sampling media Isocyanate Sampling Filter Kit - GFF (37 mm, open-faced) coated with 1 mg 1-(2-pyridyl)piperazine [SLTC103]
Sampling time*
 

15 min
Sampling volume (TWA)*
 

15 L
Sampling flow rate (TWA)*
 

1 L/min
Sampling volume (STEL/Peak/C)*
 

 
Sampling flow rate (STEL/Peak/C)*
 

 
Analytical method instruments UHPLC
Method reference OSHA 5002 (fully validated)
Notes
 

Refrigerate coated filters until used. Sample open-faced!!
Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
 

 
Bulk Method
 

 

On-Site Screening Techniques
Device Detector tube Hazard Assessment Test Kit for Aromatic Isocyanates
Model/Type Dräger - Toluene diisocyanate 0.02/a, 6724501 769-1002
Sampling information
(see manufacturer instructions) 		25 strokes, approx 0.02-0.2 ppm range, uncertainty 30% Isocyanate Surface and Dermal Sampling, Hazard Assessment Test Kit for Aromatic Isocyanates

Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

 REL-TWA
 

 

 TLV-TWA
 

0.001 ppm (inhalable fraction and vapor) [2015]

 PEL-TWA
 

 
PEL-STEL
 

 

 REL-STEL
 

 

 TLV-STEL
 

0.005 ppm (inhalable fraction and vapor) [2015]

 PEL-STEL
 

 
PEL-C
 

 

 REL-C
 

 

 TLV-C
 

 

 PEL-C
 

 
Skin notation
 

NA

 Skin notation
 

NA

 Skin notation
 

Y

 Skin notation
 

NA
Notes:

See 2,4-TOLUENE-DIISOCYANATE

 Notes:
 

Not established

 Notes:
 

dermal sensitizer (DSEN), respiratory sensitizer (RSEN)

 Notes:
 

Not established
Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: IARC-2B, NIOSH-Ca, NTP-R Notes:
 

 
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

0.01 ppm/0.15 ppm/0.6 ppm

Additional Resources and Literature References

Last Updated Date : 04/02/2025