2,4-TOLUENE-DIISOCYANATE†

Chemical Identification
Chemical Identification
CAS # 584-84-9
Formula
 

C₉H₆N₂O₂

Synonyms
 

2,4-diisocyanate-1-methylbenzene; TDI; 2,4-TDI; 2,4-toluene diisocyanate

Physical Properties
Physical Properties
Physical description Colorless to pale-yellow solid or liquid (above 71°F) with a sharp, pungent odor.
Boiling point 484°F Molecular weight 174.2
Freezing point/melting point 67.1-70.7°F Vapor pressure 0.01 mmHg at 77°F
Flash point 270°F for an 80/20% 2,4/ 2,6 TDI mixture Vapor density 6
Specific gravity 1.2244 at 68°F Ionization potential
Lower explosive limit (LEL) 0.9% Upper explosive limit (UEL) 9.5%
NFPA health rating 3 NFPA fire rating 1
NFPA reactivity rating 2 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 2470
Sampling group
Sampler/Sampling media Isocyanate Sampling Filter Kit - GFF (37 mm, open-faced) coated with 1 mg 1-(2-pyridyl)piperazine [SLTC103]
Sampling time*
 

15 min

Sampling volume (TWA)*
 

15 L

Sampling flow rate (TWA)*
 

1 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments HPLC
Method reference OSHA 5002 (fully validated)
Notes
 

Refrigerate coated filters until used. Sample open-faced!!

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device Detector tube
Model/Type Dräger - Toluene diisocyanate 0.02/a, 6724501
Sampling information
(see manufacturer instructions)
25 strokes, approx 0.02-0.2 ppm range, uncertainty 30%
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

 

TLV-TWA
 

0.001 ppm (inhalable fraction and vapor) [2015]

PEL-TWA
 

0.005 ppm (0.04 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

0.005 ppm [2015]

PEL-STEL
 

 

PEL-C
 

0.02 ppm (0.14 mg/m³)

REL-C
 

 

TLV-C
 

 

PEL-C
 

0.02 ppm (0.15 mg/m³)

Skin notation
 

N

Skin notation
 

N

Skin notation
 

Y

Skin notation
 

N

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A, NIOSH Potential Occupational Carcinogens

Notes:
 

dermal sensitizer (DSEN), respiratory sensitizer (RSEN)

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

2.5 ppm

Carcinogenic classifications: IARC-2B, NIOSH-Ca, NTP-R, TLV-A3 Notes:
 

Ca

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

0.01 ppm/0.15 ppm/0.6 ppm

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Toluene-2,4-diisocyanate

NIOSH: Pocket Guide to Chemical Hazards - Toluene-2,4-diisocyanate

Literature References

 

Last Updated Date : 04/19/2021