2-PENTANONE (METHYL PROPYL KETONE)†

Chemical Identification
Chemical Identification
CAS # 107-87-9
Formula

C₅H₁₀O

Synonyms

ethyl acetone; methyl propyl ketone; MPK

Physical Properties
Physical Properties
Physical description Colorless to water-white liquid with a characteristic acetone-like odor.
Boiling point 215°F Molecular weight 86.1
Freezing point/melting point -108°F Vapor pressure 12 mmHg
Flash point 45°F Vapor density 3
Specific gravity 0.81 Ionization potential 9.39 eV
Lower explosive limit (LEL) 1.5% Upper explosive limit (UEL) 8.2%
NFPA health rating 2 NFPA fire rating 3
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 2010
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*

480 min

Sampling volume (TWA)*

1-10 L

Sampling flow rate (TWA)*

0.01-0.2 L/min

Sampling volume (STEL/Peak/C)*

3 L

Sampling flow rate (STEL/Peak/C)*

0.2 L/min

Analytical method instruments GC-FID
Method reference NIOSH 1300 (fully validated)
Notes
 

 

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

200 ppm (700 mg/m³)

REL-TWA
 

150 ppm (530 mg/m³)

TLV-TWA
 

 

PEL-TWA
 

200 ppm (700 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

150 ppm [2006]

PEL-STEL
 

250 ppm (875 mg/m³)

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

1500 ppm

Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Methyl propyl ketone

NIOSH: Pocket Guide to Chemical Hazards - 2-Pentanone

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Methyl propyl ketone. See annual publication for most recent information.
  • Mathews, J.M., Raymer, J.H., Etheridge, A.S., Velez, G.R. and Bucher, J.R.: Do endogenous volatile organic chemicals measured in breath reflect and maintain CYP2E1 levels in vivo? Toxicol. Appl. Pharmacol. 146(2): 255-260, 1997.
  • Pohanish, R.P. (editor): 2-Pentanone. Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1808-1810.

Last Updated Date : 12/15/2020