METHYL FORMATE†

Chemical Identification
Chemical Identification
CAS # 107-31-3
Formula
 

C₂H₄O₂

Synonyms
 

methyl ester of formic acid; methyl methanoate

Physical Properties
Physical Properties
Physical description Colorless liquid with a pleasant odor.
Boiling point 89°F Molecular weight 60.1
Freezing point/melting point -148°F Vapor pressure 476 mmHg
Flash point -26°F Vapor density 2.07
Specific gravity 0.98 Ionization potential 10.82 eV
Lower explosive limit (LEL) 4.5% Upper explosive limit (UEL) 23%
NFPA health rating 2 NFPA fire rating 4
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1770
Sampling group
Sampler/Sampling media Anasorb 747 (400/200 mg) [SKC 226-83]
Sampling time*
 

 

Sampling volume (TWA)*
 

3 L

Sampling flow rate (TWA)*
 

0.05 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments GC-FID
Method reference OSHA PV2041 (partially validated)
Notes
 

Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible.

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

100 ppm (250 mg/m³)

REL-TWA
 

100 ppm (250 mg/m³)

TLV-TWA
 

50 ppm [2014]

PEL-TWA
 

100 ppm (250 mg/m³)

PEL-STEL
 

 

REL-STEL
 

150 ppm (375 mg/m³)

TLV-STEL
 

100 ppm [2014]

PEL-STEL
 

150 ppm (375 mg/m³)

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

N

Skin notation
 

N

Skin notation
 

Y

Skin notation
 

N

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

4500 ppm

Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Methyl formate

NIOSH: Pocket Guide to Chemical Hazards - Methyl formate

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Methyl formate. See annual publication for most recent information.
  • Nihlen, A. and Droz, P.O.: Toxicokinetic modeling of methyl formate exposure and implications for biological monitoring. Int. Arch. Occup. Environ. Health 73(7): 479-487, 2000.
  • Peng, H.M., Raner, G.M., Vaz, A.D. and Coon, M.J.: Oxidative cleavage of esters and amides to carbonyl products by cytochrome P450. Arch. Biochem. Biophys. 318(2):333-339, 1995.
  • Pohanish, R.P. (editor): Methyl Formate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1572-1573.

Last Updated Date : 01/05/2021