1. OSHA Occupational Chemical Database
  2. BROMOFORM
Label abbreviations descriptions

BROMOFORM†

Chemical Identification
Chemical Identification
CAS # 75-25-2
Formula

CHBr₃
Synonyms

methyl tribromide; tribromomethane
Physical Properties
Physical Properties
Physical description Colorless to yellow liquid with a chloroform-like odor.
Boiling point 301°F Molecular weight 252.8
Freezing point/melting point 47°F Vapor pressure 5 mmHg
Flash point Vapor density 8.7
Specific gravity 2.89 Ionization potential 10.48 eV
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0400
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*
Sampling volume (TWA)*

10 L
Sampling flow rate (TWA)*

0.2 L/min
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference NIOSH 1003 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media

Wipe with charcoal pad, seal in glass vial for shipment. [3M 3500]
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

0.5 ppm (5 mg/m³)

 REL-TWA

0.5 ppm (5.2 mg/m³)

 TLV-TWA

0.5 ppm [2008]

 PEL-TWA

0.5 ppm (5 mg/m³)
PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

Y

 Skin notation

Y

 Skin notation

N

 Skin notation

Y
Notes:

See 29 CFR 1910.1000 Table Z-1.

 Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

850 ppm
Carcinogenic classifications: EPA-B2, IARC-3, TLV-A3 Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Bromoform

NIOSH: Pocket Guide to Chemical Hazards - Bromoform

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Bromoform. See annual publication for most recent information.
  • EPA Air Toxics Website: Bromoform. U.S. Environmental Protection Agency Technology Transfer Network.
  • Fantuzzi, G., Righi, E., Predieri, G., Ceppelli, G., Gobba, F. and Aggassotti, G.: Occupational exposure to trihalomethanes in indoor swimming pools. Sci. Total Environ. 264(3): 257-265, 2001.
  • Kash, T.L., Jenkins, A. and Harrison, N.L.: Molecular volume determines the activity of the halogenated alkane bromoform at wild-type and mutant GABA(A) receptors. Brain Res. 960(1-2): 36-41, 2003.
  • Pohanish, R.P. (editor): Bromoform. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 377-379.
  • Anders, M.W., Stevens, J.L., Sprague, R.W., Shaath, Z. and Ahmed, A.E.: Metabolism of haloforms to carbon monoxide. II. In vivo studies. Drug Metab. Dispos. 6(5): 556-560, 1978.
  • Xu, X., Mariano, T.M., Laskin, J.D. and Weisel, C.P.: Percutaneous absorption of trihalomethanes, haloacetic acids, and haloketones. Toxicol. Appl. Pharmacol. 184(1): 19-26, 2002.

Last Updated Date : 12/18/2020