ACETALDEHYDE†

Chemical Identification
Chemical Identification
CAS # 75-07-0
Formula

C₂H₄O

Synonyms

acetic aldehyde; ethanal; ethyl aldehyde

Physical Properties
Physical Properties
Physical description Colorless liquid or gas (above 69°F) with a pungent, fruity odor.
Boiling point 69°F Molecular weight 44.1
Freezing point/melting point -190°F Vapor pressure 740 mmHg
Flash point -36°F Vapor density 1.52
Specific gravity 0.79 Ionization potential 10.22 eV
Lower explosive limit (LEL) 4.0% Upper explosive limit (UEL) 60%
NFPA health rating 2 NFPA fire rating 4
NFPA reactivity rating 2 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0010
Sampling group
Sampler/Sampling media XAD-2 tube (450/225 mg) coated with 10% 2-(hydroxymethyl)piperidine [SKC 226-27]
Sampling time*

60 min

Sampling volume (TWA)*

3 L

Sampling flow rate (TWA)*

0.05 L/min

Sampling volume (STEL/Peak/C)*

0.75 L

Sampling flow rate (STEL/Peak/C)*

0.05 L/min

Analytical method instruments GC-NPD
Method reference OSHA 68 (fully validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device Detector tube Detector tube Detector tube
Model/Type Dräger - Acetaldehyde 100/a, 6726665 Matheson-Kitagawa 8014-133SB Gastec 92
Sampling information
(see manufacturer instructions)
20 strokes, approx 10-1000 ppm range, uncertainty 25% follow mfr instructions, 1-140 ppm range 1-4 strokes, 2-750 ppm range, uncertainty 16.4% for 10 to 100 ppm, 8.2% for 100 to 300 ppm
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

200 ppm (360 mg/m³)

REL-TWA TLV-TWA PEL-TWA
PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C

25 ppm [2013]

PEL-C

25 ppm (45 mg/m³)

Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes:

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 18 ppm). See Appendix A and Appendix C - Supplementary

Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

2000 ppm

Carcinogenic classifications: TLV-A2, IARC-2B, NIOSH-Ca, NTP-R, EPA-B2 Notes:

Ca

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

10 ppm/200 ppm/1000 ppm

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Acetaldehyde

NIOSH: Pocket Guide to Chemical Hazards - Acetaldehyde

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Acetaldehyde. See annual publication for most recent information.
  • EPA Air Toxics Website: Acetaldehyde. US Environmental Protection Agency Technology Transfer Network.
  • Oyama, T., Isse, T., Ogawa, M., Muto, M., Uchiyama, I. and Kawamoto, T.: Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice. Front. Biosci. 12: 1927-1934, 2007.
  • Pohanish, R.P. (editor): Acetaldehyde. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 23-26.
  • Prieto, L., Gutierrez, V., Cervera, A. and Linana, J.: Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness. J. Investig. Allergol. Clin. Immunol. 12(2): 91-98, 2002.

Last Updated Date : 12/15/2020