ACETONITRILE†

Chemical Identification
CAS # 75-05-8
Formula

CH₃CN

Synonyms

cyanomethane; ethyl nitrile; methyl cyanide; ACN

Physical Properties
Physical description Colorless liquid with an aromatic odor.
Boiling point 179°F Molecular weight 41.1
Freezing point/melting point -49°F Vapor pressure 73 mmHg
Flash point 42°F (open cup) Vapor density 1.42
Specific gravity 0.787 Ionization potential 12.20 eV
Lower explosive limit (LEL) 3.0% Upper explosive limit (UEL) 16%
NFPA health rating 2 NFPA fire rating 3
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0060
Sampling group
Sampler/Sampling media CSC tube (400/200 mg) [SKC 226-09]
Sampling time*
Sampling volume (TWA)*

1-25 L

Sampling flow rate (TWA)*

0.01-0.2 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference NIOSH 1606 (fully validated)
Notes

Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible.

Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

40 ppm (70 mg/m³)

REL-TWA

20 ppm (34 mg/m³)

TLV-TWA

20 ppm [1996]

PEL-TWA

40 ppm (70 mg/m³)

PEL-STEL REL-STEL TLV-STEL PEL-STEL

60 ppm (105 mg/m³)

PEL-C REL-C TLV-C PEL-C
Skin notation

N

Skin notation

N

Skin notation

Y

Skin notation

Y

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

500 ppm

Carcinogenic classifications: TLV-A4, EPA-CBD; D Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Last Updated Date : 09/21/2022