1. OSHA Occupational Chemical Database
  2. BUTADIENE (1,3-BUTADIENE)
Label abbreviations descriptions

BUTADIENE (1,3-BUTADIENE)‡

Chemical Identification
Chemical Identification
CAS # 106-99-0
Formula

C₄H₆
Synonyms

biethylene; bivinyl, butadiene; divinyl, erythrene; vinylethylene
Physical Properties
Physical Properties
Physical description Colorless gas with a mild aromatic or gasoline-like odor.
Boiling point 24°F Molecular weight 54.1
Freezing point/melting point -164°F Vapor pressure 2.4 atm
Flash point -105°F (liquid) Vapor density 1.88
Specific gravity 0.621 at 68°F Ionization potential 9.07 eV
Lower explosive limit (LEL) 2.0% Upper explosive limit (UEL) 12.0%
NFPA health rating 2 NFPA fire rating 4
NFPA reactivity rating 2 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0410
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) coated with 10% t-butylcatechol [SKC 226-73]
Sampling time*

60 min
Sampling volume (TWA)*

3 L
Sampling flow rate (TWA)*

0.05 L/min
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA 56 (fully validated)
Notes

Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible.
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device CMS Chip
Model/Type Butadiene, 1-25 ppm range
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

1 ppm (2.21 mg/m³)

 REL-TWA TLV-TWA

2 ppm [1994]

 PEL-TWA

1 ppm (2.2 mg/m³)
PEL-STEL

5 ppm (11 mg/m³)

 REL-STEL TLV-STEL PEL-STEL

5 ppm (11 mg/m³)
PEL-C REL-C TLV-C PEL-C
Skin notation

N

 Skin notation

N

 Skin notation

N

 Skin notation

NA
Notes:

See 29 CFR 1910.1051, 1,3-Butadiene and 29 CFR 1910.19, Special provisions for air contaminants.

 Notes:

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 0.19 ppm). See Appendix A

 Notes: Notes:

See California Code of Regulations, Title 8, Section 5201. 1,3-Butadiene
Health factors:  See NIH-NLM PubChem. IDLH

2000 ppm
Carcinogenic classifications: EPA-CaH (inhaled), IARC-1, NIOSH-Ca, NTP-K, OSHA-Ca, TLV-A2 Notes:

Ca; 10% of LEL
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

10 ppm/500 ppm/5000 ppm
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - 1,3-Butadiene

NIOSH: Pocket Guide to Chemical Hazards - 1,3-Butadiene

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 1,3-Butadiene. See annual publication for most recent information.
  • Technology Transfer Network Air Toxics Website: 1,3-Butadiene.
  • Begemann, P., Sram, R.J. and Neumann, H.G.: Hemoglobin adducts of epoxybutene in workers occupationally exposed to 1,3-butadiene. Arch. Toxicol. 74(11): 680-687, 2001.
  • Benowitz, N.L., Peng, M. and Jacob, P., III: Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism. Clin. Pharmacol. Ther. 74(5): 468-474, 2003.
  • Pohanish, R.P. (editor): 1,3-Butadiene. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 384-386.

Last Updated Date : 12/18/2020