ETHYL 2-CYANOACRYLATE

Chemical Identification
CAS #	7085-85-0
Formula	C₆H₇NO₂
Synonyms	2-cyanoacrylate acid, ethyl ester; ECA; ethyl cyanoacrylate; ethyl ⍺-cyanoacrylate; 2-propenoic acid, 2-cyano, ethyl ester

Physical Properties
Physical description	Clear colorless liquid with irritating, sweet, ester-like odor
Boiling point	54-56°C	Molecular weight	125.14
Freezing point/melting point		Vapor pressure	<2 mmHg at 25°C
Flash point		Vapor density
Specific gravity		Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	E108
Sampling group
Sampler/Sampling media	XAD-7 (80/40 mg sections, 20/60 mesh) coated with 10% phosphoric acid [SKC 226-98]
Sampling time^*	120 min
Sampling volume (TWA)^*	12 L
Sampling flow rate (TWA)^*	0.1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	HPLC
Method reference	OSHA 55 (fully validated)
Notes	Samples must be kept at reduced temperature and shipped to lab cold.
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA		TLV-TWA	0.2 ppm [2017]	PEL-TWA	0.2 ppm (1.02 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL	1 ppm [2017]	PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	NA	Skin notation	N	Skin notation	N
Notes: Not established		Notes: Not established		Notes: dermal sensitization (DSEN), respiratory sensitization (RSEN)		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: Not listed		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Not listed

NIOSH: Pocket Guide to Chemical Hazards - Not listed

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Cyanoacrylate, Ethyl [7085-85-0] and Methyl [137-05-3]. See annual publication for most recent information.
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: UD3330050
Bruze, M., Björkner, B. and Lepoittevin, J.-P.: Occupational contact dermatitis from ethyl cyanoacrylate. Contact Dermatitis 32(3): 156-159, 1995.
Constandt, L., Hecke, E.V., Naeyaert, J.M. and Goossens, A.: Screeing for contact allergy to artificial nails. Contact Dermatitis 52(2): 73-77, 2005.
Gagnaire, F., Marignac, B., Morel, G., Nunge, H. and Grossmann, S.: Sensory irritation due to methyl-2-cyanoacrylate, ethyl-2-cyanoacrylate, isopropyl-2-cyanoacrylate and 2-methoxyethyl-2-cyanoacrylate in mice. Ann. Occup. Hyg. 47(4): 297-304, 2003.
Goodman, M., et al.: Epidemiologic study of pulmonary obstruction in workers occupationally exposed to ethyl and methyl cyanoacrylate. J. Toxicol. Environ. Health A 59(3): 135-163, 2000.
Paustenbach, D., Burke, M.L., Shum, M. and Kalmes, R.: Airborne concentrations of ethyl and methyl cyanoacrylate in the workplace. AIHAJ 62(1): 70-79, 2001.

Last Updated Date : 12/19/2018

ETHYL 2-CYANOACRYLATE

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References