ETHYL 2-CYANOACRYLATE

Chemical Identification
Chemical Identification
CAS # 7085-85-0
Formula

C₆H₇NO₂

Synonyms
 

2-cyanoacrylate acid, ethyl ester; ECA; ethyl cyanoacrylate; ethyl ⍺-cyanoacrylate; 2-propenoic acid, 2-cyano, ethyl ester

Physical Properties
Physical Properties
Physical description Clear colorless liquid with irritating, sweet, ester-like odor
Boiling point 54-56°C Molecular weight 125.14
Freezing point/melting point Vapor pressure <2 mmHg at 25°C
Flash point Vapor density
Specific gravity Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) E108
Sampling group
Sampler/Sampling media XAD-7 (80/40 mg sections, 20/60 mesh) coated with 10% phosphoric acid [SKC 226-98]
Sampling time*
 

120 min

Sampling volume (TWA)*
 

12 L

Sampling flow rate (TWA)*
 

 0.1 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments HPLC
Method reference OSHA 55 (fully validated)
Notes
 

Samples must be kept at reduced temperature and shipped to lab cold.

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

 

TLV-TWA
 

0.2 ppm [2017]

PEL-TWA
 

0.2 ppm (1.02 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

1 ppm [2017]

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

N

Skin notation
 

N

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

dermal sensitization (DSEN), respiratory sensitization (RSEN)

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Not listed

NIOSH: Pocket Guide to Chemical Hazards - Not listed

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Cyanoacrylate, Ethyl [7085-85-0] and Methyl [137-05-3]. See annual publication for most recent information.
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: UD3330050
  • Bruze, M., Björkner, B. and Lepoittevin, J.-P.: Occupational contact dermatitis from ethyl cyanoacrylate. Contact Dermatitis 32(3): 156-159, 1995.
  • Constandt, L., Hecke, E.V., Naeyaert, J.M. and Goossens, A.: Screeing for contact allergy to artificial nails. Contact Dermatitis 52(2): 73-77, 2005.
  • Gagnaire, F., Marignac, B., Morel, G., Nunge, H. and Grossmann, S.: Sensory irritation due to methyl-2-cyanoacrylate, ethyl-2-cyanoacrylate, isopropyl-2-cyanoacrylate and 2-methoxyethyl-2-cyanoacrylate in mice. Ann. Occup. Hyg. 47(4): 297-304, 2003.
  • Goodman, M., et al.: Epidemiologic study of pulmonary obstruction in workers occupationally exposed to ethyl and methyl cyanoacrylate. J. Toxicol. Environ. Health A 59(3): 135-163, 2000.
  • Paustenbach, D., Burke, M.L., Shum, M. and Kalmes, R.: Airborne concentrations of ethyl and methyl cyanoacrylate in the workplace. AIHAJ 62(1): 70-79, 2001.

Last Updated Date : 12/19/2018