ACETONE†

Chemical Identification
Chemical Identification
CAS # 67-64-1
Formula

C₃H₆O

Synonyms

dimethyl ketone; ketone propane; 2-propanone

Physical Properties
Physical Properties
Physical description Colorless liquid with a fragrant, mint-like odor.
Boiling point 133°F Molecular weight 58.1
Freezing point/melting point -137°F Vapor pressure 180 mmHg
Flash point 0°F Vapor density
Specific gravity 0.791 Ionization potential 9.69 eV
Lower explosive limit (LEL) 2.5% Upper explosive limit (UEL) 12.8%
NFPA health rating 1 NFPA fire rating 3
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0040
Sampling group
Sampler/Sampling media ORBO™ 91 Carbosieve® S-III (130/65) [Supelco 20360]
Sampling time*

60 min

Sampling volume (TWA)*

3 L

Sampling flow rate (TWA)*

0.05 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA 69 (fully validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device CMS Chip Detector tube
Model/Type Acetone, 40-600 ppm range Gastec 151
Sampling information
(see manufacturer instructions)
0.05-2%
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

1000 ppm (2400 mg/m³)

REL-TWA

250 ppm (590 mg/m³)

TLV-TWA

250 ppm [2014]

PEL-TWA

500 ppm (1200 mg/m³)

PEL-STEL REL-STEL TLV-STEL

500 ppm [2014]

PEL-STEL

750 ppm (1780 mg/m³)

PEL-C REL-C TLV-C PEL-C

3000 ppm

Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

2500 ppm (10% LEL)

Carcinogenic classifications: TLV-A4, EPA-I Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Acetone

NIOSH: Pocket Guide to Chemical Hazards - Acetone

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Acetone. See annual publication for most recent information.
  • ATSDR: Toxicological Profile for Acetone. May 1994.
  • California Occupational Safety & Health Standards Board Initial and Final Statement of Reasons. July 6, 2006.
  • Dietz, DD, Leininger, JR, Rauckman, EJ, et al.: Toxicity studies of acetone administered in the drinking water of rodents. Fund. Appl. Toxicol. 17:347-360, 1991.
  • EPA: Integrated Risk Information System - Acetone (CASRN 67-64-1). 2003.
  • NIOSH: Criteria for a Recommended Standard - Occupational Exposure to Ketones. June 1978.
  • NIOSH: Occupational Health Guideline for Acetone. 1988.
  • Wysocki, C.J., Dalton, P., Brody, M.J. and Lawley, H.J.: Acetone odor and irritation thresholds obtained from acetone-exposed factory workers and from control (occupationally unexposed) subjects. Am. Ind. Hyg. Assoc. J. 58(10): 704-711, 1997.

Last Updated Date : 12/15/2020