ALLYL GLYCIDYL ETHER (AGE) | Occupational Safety and Health Administration

ALLYL GLYCIDYL ETHER (AGE)†

Chemical Identification
CAS #	106-92-3
Formula	C₆H₁₀O₂
Synonyms	AGE; 1-allyloxy-2,3-epoxypropane; glycidyl allyl ether; [(2-propenyloxy)methyl] oxirane

Physical Properties
Physical description	Colorless liquid with a pleasant odor.
Boiling point	309°F	Molecular weight	114.2
Freezing point/melting point	-148°F [forms glass]	Vapor pressure	2 mmHg
Flash point	135°F	Vapor density	3.94
Specific gravity	0.97	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0145
Sampling group
Sampler/Sampling media	Tenax® GC tube (100/50 mg) [Supelco 20832-U]
Sampling time^*
Sampling volume (TWA)^*	1.5-8 L
Sampling flow rate (TWA)^*	0.01-0.2 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	NIOSH 2545 (fully validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	5 ppm (22 mg/m³)	TLV-TWA		PEL-TWA	0.2 ppm (0.93 mg/m³)
PEL-STEL		REL-STEL	10 ppm (44 mg/m³)	TLV-STEL		PEL-STEL
PEL-C	10 ppm (45 mg/m³)	REL-C		TLV-C		PEL-C
Skin notation	N	Skin notation	Y	Skin notation	N	Skin notation	Y
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes:		Notes: Visit the ACGIH TLV site for specific data		Notes:
Health factors: See NIH-NLM PubChem.		IDLH	50 ppm
Carcinogenic classifications: TLV-A4		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Allyl glycidyl ether

NIOSH: Pocket Guide to Chemical Hazards - Allyl glycidyl ether

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Allyl glycidyl ether. See annual publication for most recent information.
Dooms-Goossens, A., Bruze, M., Buysse, L., Fregert, S., Gruvberger, B. and Stals, H.: Contact allergy to allyl glycidyl ether present as an impurity in 3-glycidyloxypropyltrimethoxysilane, a fixing additive in silicone and polyurethane resins. Contact Dermatitis 33(1): 17-19, 1995.
National Toxicology Program: NTP Toxicology and Carcinogenesis Studies of Allyl Glycidyl Ether (CAS No. 106-92-3) in Osborne-Mendel Rats and B6C3F1 Mice (Inhalational Studies). Natl. Toxicol. Program Tech. Rep. Ser. 376: 1-219, 1990.
Pérez, H.L. and Osterman-Golkar, S.: Biotransformation of the double bond in allyl glycidyl ether to an epoxide ring. Evidence from hemoglobin adducts in mice. Chem. Biol. Interact. 125(1): 17-28, 2000.
Pina, K. and Segerbäch, D.: 32P-Postlabeling of DNA adducts formed by allyl glycidyl ether in vitro and in vivo. Carcinogenesis 18(8): 1457-1462, 1997.
Pohanish, R.P. (editor): Allyl Glycidyl Ether. In, Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 101-103.

Last Updated Date : 03/27/2024

ALLYL GLYCIDYL ETHER (AGE)†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References