EPICHLOROHYDRIN (1-CHLORO-2,3-EPOXYPROPANE)†
Chemical Identification | |
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CAS # | 106-89-8 |
Formula |
C₃H₅ClO |
Synonyms |
2-chloropropylene oxide; β-chloropropylene oxide; 1-chloro-2,3-epoxypropane |
Physical Properties | |||
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Physical description | Colorless liquid with a slightly irritating, chloroform-like odor. | ||
Boiling point | 242°F | Molecular weight | 92.5 |
Freezing point/melting point | -54°F | Vapor pressure | 13 mmHg |
Flash point | 93°F | Vapor density | 3.29 |
Specific gravity | 1.18 | Ionization potential | 10.60 eV |
Lower explosive limit (LEL) | 3.8% | Upper explosive limit (UEL) | 21% |
NFPA health rating | 4 | NFPA fire rating | 3 |
NFPA reactivity rating | 2 | NFPA special instruction | |
Vapor hazard ratio (VHR) | |||
Historical exceedance percentage | |||
Target organs |
Monitoring Methods Used by OSHA | ||||||
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Analyte code (IMIS no.) | 0645 | |||||
Sampling group | ||||||
Sampler/Sampling media | CSC tube (100/50 mg) [SKC 226-01] | |||||
Sampling time* | 480 min |
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Sampling volume (TWA)* | 2-30 L |
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Sampling flow rate (TWA)* | 0.01-0.2 L/min |
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Sampling volume (STEL/Peak/C)* |
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Sampling flow rate (STEL/Peak/C)* |
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Analytical method instruments | GC-FID | |||||
Method reference | NIOSH 1010 (fully validated) | |||||
Notes |
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Special requirements |
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* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
Wipe Method | |
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Sampler/Sampling media | Wipe with charcoal pad, seal in glass vial for shipment. [3M 3500] |
Bulk Method |
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On-Site Screening Techniques | ||||||
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Device | ||||||
Model/Type | ||||||
Sampling information (see manufacturer instructions) |
Exposure Limits | |||||||
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OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
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PEL-TWA |
5 ppm (19 mg/m³) |
REL-TWA |
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TLV-TWA |
0.5 ppm [1994] |
PEL-TWA |
0.05 ppm (0.19 mg/m³) |
PEL-STEL |
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REL-STEL |
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TLV-STEL |
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PEL-STEL |
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PEL-C |
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REL-C |
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TLV-C |
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PEL-C |
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Skin notation |
Y |
Skin notation |
N |
Skin notation |
Y |
Skin notation |
Y |
Notes: |
Notes:
CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 2.5 mg/m3). See Appendix A. |
Notes:
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Notes:
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Health factors: See NIH-NLM PubChem. | IDLH |
75 ppm |
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Carcinogenic classifications: IARC-2A, NIOSH-Ca, NTP-R, TLV-A3, EPA-B2 |
Notes:
Ca |
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AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
5 ppm/20 ppm/100 ppm |
Additional Resources and Literature References |
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NOAA: CAMEO Chemicals - 1-Chloro-2,3-epoxypropane NIOSH: Pocket Guide to Chemical Hazards - Epichlorohydrin Literature References
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Last Updated Date : 12/28/2020