EPICHLOROHYDRIN (1-CHLORO-2,3-EPOXYPROPANE)†

Chemical Identification
CAS # 106-89-8
Formula
 

C₃H₅ClO

Synonyms
 

2-chloropropylene oxide; β-chloropropylene oxide; 1-chloro-2,3-epoxypropane

Physical Properties
Physical description Colorless liquid with a slightly irritating, chloroform-like odor.
Boiling point 242°F Molecular weight 92.5
Freezing point/melting point -54°F Vapor pressure 13 mmHg
Flash point 93°F Vapor density 3.29
Specific gravity 1.18 Ionization potential 10.60 eV
Lower explosive limit (LEL) 3.8% Upper explosive limit (UEL) 21%
NFPA health rating 4 NFPA fire rating 3
NFPA reactivity rating 2 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0645
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*
 

480 min

Sampling volume (TWA)*
 

2-30 L

Sampling flow rate (TWA)*
 

0.01-0.2 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments GC-FID
Method reference NIOSH 1010 (fully validated)
Notes
 

 

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Sampler/Sampling media
 

Wipe with charcoal pad, seal in glass vial for shipment. [3M 3500]

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

5 ppm (19 mg/m³)

REL-TWA
 

 

TLV-TWA
 

0.5 ppm [1994]

PEL-TWA
 

0.05 ppm (0.19 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

Y

Skin notation
 

N

Skin notation
 

Y

Skin notation
 

Y

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 2.5 mg/m3). See Appendix A.

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

75 ppm

Carcinogenic classifications: IARC-2A, NIOSH-Ca, NTP-R, TLV-A3, EPA-B2 Notes:
 

Ca

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

5 ppm/20 ppm/100 ppm

Last Updated Date : 12/28/2020