1. OSHA Occupational Chemical Database
  2. AMITROLE
Label abbreviations descriptions

AMITROLE

Chemical Identification
Chemical Identification
CAS # 61-82-5
Formula

C₂H₄N₄
Synonyms

aminotriazole; 3-aminotriazole; 2-amino-1,3,4-triazole; 3-amino-1,2,4-triazole
Physical Properties
Physical Properties
Physical description Colorless to white, crystalline powder.
Boiling point Molecular weight 84.1
Freezing point/melting point 318°F Vapor pressure <0.000008 mmHg
Flash point Vapor density
Specific gravity 1.14 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 1 NFPA fire rating 1
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) A176
Sampling group
Sampler/Sampling media Midget fritted glass bubbler (MFGB) containing 10 mL Distilled Water [Infrequently Requested Method - OSHA staff please contact SLTC before sampling 801-233-4900]
Sampling time*
Sampling volume (TWA)*

60 L
Sampling flow rate (TWA)*

1 L/min
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments HPLC-UV
Method reference OSHA PV2006 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA

0.2 mg/m³

 TLV-TWA

0.2 mg/m³ [1983]

 PEL-TWA

0.2 mg/m³
PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

NA

 Skin notation

N

 Skin notation

N

 Skin notation

N
Notes:

Not established

 Notes:

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A, NIOSH Potential Occupational Carcinogens.

 Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: IARC-3, NIOSH-Ca, NTP-R, TLV-A3 Notes:

Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Amitrole

NIOSH: Pocket Guide to Chemical Hazards - Amitrole

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Amitrole. See annual publication for most recent information.
  • Environmental Protection Agency: R.E.D. Facts: Amitrole. Publication No. EPA-738-F-96-002 (August) 1996, 13 pp.
  • Hurley, P.M.: Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents. Environ. Health Perspect. 106(8): 437-445, 1998.
  • Pohanish, R.P. (editor): 3-Amino-1,2,4-Triazole. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 143-144.
  • Putnam, C.D., Arvai, A.S., Bourne, Y. and Tainer, J.A.: Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism. J. Mol. Biol. 296(1): 295-309, 2000.

Last Updated Date : 12/17/2020