O-METHYLCYCLOHEXANONE†

Chemical Identification
Chemical Identification
CAS # 583-60-8
Formula

CH₃C₆H₉O

Synonyms

2-methylcyclohexanone

Physical Properties
Physical Properties
Physical description Colorless liquid with a weak, peppermint-like odor.
Boiling point 329°F Molecular weight 112.2
Freezing point/melting point 6.8°F Vapor pressure 1 mmHg
Flash point 118°F Vapor density
Specific gravity 0.93 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 2 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1765
Sampling group
Sampler/Sampling media Porapak Q tube (150/75 mg) [SKC 226-115]
Sampling time*
Sampling volume (TWA)*

1-6 L

Sampling flow rate (TWA)*

0.01-0.05 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference NIOSH 2521 (fully validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

100 ppm (460 mg/m³)

REL-TWA
 

50 ppm (230 mg/m³)

TLV-TWA
 

50 ppm [1970]

PEL-TWA
 

50 ppm (230 mg/m³)

PEL-STEL
 

 

REL-STEL
 

75 ppm (345 mg/m³)

TLV-STEL
 

75 ppm [1970]

PEL-STEL
 

75 ppm (345 mg/m³)

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

Y

Skin notation
 

Y

Skin notation
 

Y

Skin notation
 

Y

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

600 ppm

Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - O-Methylcyclohexanone

NIOSH: Pocket Guide to Chemical Hazards - o-Methylcyclohexanone

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - o-Methylcyclohexanone. See annual publication for most recent information.
  • Nakajin, S., Tamura, F., Takase, N. and Toyoshima, S.; Carbonyl reductase activity exhibited by pig testicular 20 β-hydroxysteroid dehydrogenase. Biol. Pharm. Bull. 29(11): 1215-1218, 1997.
  • Newberne, P., et al.: GRAS flavoring substances 19. Food Technol. 54(6): 66-68, 70, 72-74, 76-84, 2000.
  • Pohanish, R.P. (editor): 2-Methylcyclohexanone. In, Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1549-1550.

Last Updated Date : 01/07/2021