P-DICHLOROBENZENE†

Chemical Identification
Chemical Identification
CAS # 106-46-7
Formula

C₆H₄Cl₂

Synonyms

p-DCB; 1,4-DCB; 1,4-dichlorobenzene; Dichlorocide; Paracide

Physical Properties
Physical Properties
Physical description Colorless or white crystalline solid with a mothball-like odor.
Boiling point 345°F Molecular weight 147.0
Freezing point/melting point 128°F Vapor pressure 1.3 mmHg
Flash point 150°F Vapor density 5.08
Specific gravity 1.458 Ionization potential 8.98 eV
Lower explosive limit (LEL) 2.5% Upper explosive limit (UEL)
NFPA health rating 2 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0868
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*
Sampling volume (TWA)*

1-8 L

Sampling flow rate (TWA)*

0.01-0.2 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference NIOSH 1003 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

75 ppm (450 mg/m³)

REL-TWA TLV-TWA

10 ppm [1990]

PEL-TWA

10 ppm (60 mg/m³)

PEL-STEL REL-STEL TLV-STEL PEL-STEL

110 ppm (675 mg/m³)

PEL-C REL-C TLV-C PEL-C

200 ppm

Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes:

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 1.7 ppm). See Appendix A, NIOSH Potential Occupational Carcinogens.

Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

150 ppm

Carcinogenic classifications: IARC-2B, NIOSH-Ca, NTP-R, TLV-A3 Notes:

Ca

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - P-Dichlorobenzene

NIOSH: Pocket Guide to Chemical Hazards - p-Dichlorobenzene

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - p-Dichlorobenzene. See annual publication for most recent information.
  • Bogaards, J.J.P., van Ommen., B., Wolf, C.R. and van Bladeren, P.J.: Human cytochrome P450 enzyme selectivities in the oxidation of chlorinated benzenes. Toxicol. Appl. Pharmacol. 132(1): 44-52, 1995.
  • Miyai, I., Hirono, N., Fujita, M. and Kameyama, M.: Reversible ataxia following chronic exposure to paradichlorobenzene. J. Neurol. Neurosurg. Psychiatry 51(3): 453-454, 1988.
  • Pohanish, R.P. (editor): Dichlorobenzenes. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 799-804.
  • Rosas Vazques, E., Campos Macias, P., Ochoa Tirado, J.G., Garcia Solana, C., Casanova, A. and Palomino Moncada, J.F.: Chloracne in the 1990s. Int. J. Dermatol. 35(9): 643-645, 1996.
  • Yoshida, T., et al.: Inhalation toxicokinetics of p-dichlorobenzene and daily absorption and internal accumulation in chronic low-level exposure to humans. Arch. Toxicol. 76(5-6): 306-315, 2002.

Last Updated Date : 01/08/2021