P-DICHLOROBENZENE | OSHA.gov | Occupational Safety and Health Administration

P-DICHLOROBENZENE†

Chemical Identification
CAS #	106-46-7
Formula	C₆H₄Cl₂
Synonyms	p-DCB; 1,4-DCB; 1,4-dichlorobenzene; Dichlorocide; Paracide

Physical Properties
Physical description	Colorless or white crystalline solid with a mothball-like odor.
Boiling point	345°F	Molecular weight	147.0
Freezing point/melting point	128°F	Vapor pressure	1.3 mmHg
Flash point	150°F	Vapor density	5.08
Specific gravity	1.458	Ionization potential	8.98 eV
Lower explosive limit (LEL)	2.5%	Upper explosive limit (UEL)
NFPA health rating	2	NFPA fire rating	2
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0868
Sampling group
Sampler/Sampling media	CSC tube (100/50 mg) [SKC 226-01]
Sampling time^*
Sampling volume (TWA)^*	1-8 L
Sampling flow rate (TWA)^*	0.01-0.2 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	NIOSH 1003 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	75 ppm (450 mg/m³)	REL-TWA		TLV-TWA	10 ppm [1990]	PEL-TWA	10 ppm (60 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL	110 ppm (675 mg/m³)
PEL-C		REL-C		TLV-C		PEL-C	200 ppm
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes: CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 1.7 ppm). See Appendix A, NIOSH Potential Occupational Carcinogens.		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH	150 ppm
Carcinogenic classifications: IARC-2B, NIOSH-Ca, NTP-R, TLV-A3		Notes: Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - P-Dichlorobenzene

NIOSH: Pocket Guide to Chemical Hazards - p-Dichlorobenzene

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - p-Dichlorobenzene. See annual publication for most recent information.
Bogaards, J.J.P., van Ommen., B., Wolf, C.R. and van Bladeren, P.J.: Human cytochrome P450 enzyme selectivities in the oxidation of chlorinated benzenes. Toxicol. Appl. Pharmacol. 132(1): 44-52, 1995.
Miyai, I., Hirono, N., Fujita, M. and Kameyama, M.: Reversible ataxia following chronic exposure to paradichlorobenzene. J. Neurol. Neurosurg. Psychiatry 51(3): 453-454, 1988.
Pohanish, R.P. (editor): Dichlorobenzenes. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 799-804.
Rosas Vazques, E., Campos Macias, P., Ochoa Tirado, J.G., Garcia Solana, C., Casanova, A. and Palomino Moncada, J.F.: Chloracne in the 1990s. Int. J. Dermatol. 35(9): 643-645, 1996.
Yoshida, T., et al.: Inhalation toxicokinetics of p-dichlorobenzene and daily absorption and internal accumulation in chronic low-level exposure to humans. Arch. Toxicol. 76(5-6): 306-315, 2002.

Last Updated Date : 01/08/2021

P-DICHLOROBENZENE†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References