1. OSHA Occupational Chemical Database
  2. HYDRAZINE
Label abbreviations descriptions

HYDRAZINE†

Chemical Identification
Chemical Identification
CAS # 302-01-2
Formula

N₂H₄
Synonyms

diamine; hydrazine (anhydrous); hydrazine base
Physical Properties
Physical Properties
Physical description Colorless, fuming, oily liquid with an ammonia-like odor.
Boiling point 236.3°F Molecular weight 32.05
Freezing point/melting point 36°F Vapor pressure 10 mmHg
Flash point 125.6°F Vapor density
Specific gravity 1.01 Ionization potential 8.93 eV
Lower explosive limit (LEL) 4.7% Upper explosive limit (UEL) 100%
NFPA health rating 4 NFPA fire rating 4
NFPA reactivity rating 3 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1390
Sampling group
Sampler/Sampling media 2 GFFs (37 mm) coated with sulfuric acid, in 3-piece cassette, separated by the ring section [SKC 225-9004]
Sampling time*
Sampling volume (TWA)*

240 L
Sampling flow rate (TWA)*

1 L/min
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments HPLC
Method reference OSHA 108 (fully validated)
Notes

The 2 filters are separated by the ring section of the 3-piece cassette to provide a backup portion to the sampling train.
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 
Bulk Method
Bulk Method
 

Limit the amount of bulk submitted to 1 g or 1 mL.
On-Site Screening Techniques
On-Site Screening Techniques
Device Detector tube Detector tube Detector tube
Model/Type Dräger - Hydrazine 0.2/a, 6733121 Dräger - Hydrazine 0.25/a, CH31801 Matheson-Kitagawa 8014-219S
Sampling information
(see manufacturer instructions) 		10 or 20 strokes, approx 0.1-10 ppm range, uncertainty 25% 5 or 10 strokes, 0.01-2 ppm range, uncertainty 16% for 0.1-0.5 ppm, 8% for 0.5-2 ppm follow mfr instructions, approx 0.1 ppm-10 ppm range
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

1 ppm (1.3 mg/m³)

 REL-TWA
 

 

 TLV-TWA
 

0.01 ppm [1988]

 PEL-TWA
 

0.01 ppm (0.013 mg/m³)
PEL-STEL
 

 

 REL-STEL
 

 

 TLV-STEL
 

 

 PEL-STEL
 

 
PEL-C
 

 

 REL-C
 

0.03 ppm (0.04 mg/m³) [120 minutes]

 TLV-C
 

 

 PEL-C
 

 
Skin notation
 

Y

 Skin notation
 

N

 Skin notation
 

Y

 Skin notation
 

Y
Notes:
 

See 29 CFR 1910.1000 Table Z-1.

 Notes:
 

CARCINOGEN (Ca): See Appendix A, NIOSH Potential Occupational Carcinogens.

 Notes:
 

 

 Notes:
 

 
Health factors:  See NIH-NLM PubChem. IDLH
 

50 ppm
Carcinogenic classifications: IARC-2B,NIOSH-Ca, NTP-R, TLV-A3, EPA-B2 Notes:
 

Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

0.5 ppm/5 ppm/30 ppm
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Hydrazine, anhydrous

NIOSH: Pocket Guide to Chemical Hazards - Hydrazine

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Hydrazine. See annual publication for most recent information.
  • EPA Air Toxics Website: Hydrazine U.S. Environmental Protection Agency Technology Transfer Network.
  • Reidenberg, M.M., Durant, P.J., Harris, R.A., De Boccardo, G., Lahita, R. and Stenzel, K.H.: Lupus erythematosus-like disease due to hydrazine. Am. J. Med. 75: 365-370, 1983 (malar rash, photosensitivity, antinuclear antibody, antibody to nDNA).

Last Updated Date : 01/28/2021