1,3,5-TRIGLYCIDYL-S-TRIAZINETRIONE

Chemical Identification
Chemical Identification
CAS # 2451-62-9
Formula

C₁₂H₁₅N₃O₆

Synonyms

TGIC, triglycidyl isocyanurate, 1,3,5-triglycidyl isocyanurate, TGT, glycidyl isocyanurate, tris(epoxypropyl)isocyanurate, s-triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(2,3-epoxypropyl)-s-triazine-2,4,6(1H,3H,5H)-trione. [1,3,5-triglycidyl isocyanurate (TGIC) has two stereoisomers, α and β]

Physical Properties
Physical Properties
Physical description White crystalline solid.
Boiling point Molecular weight 297.27
Freezing point/melting point 203-208°F Vapor pressure
Flash point Vapor density
Specific gravity Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) T405
Sampling group
Sampler/Sampling media GFF (37 mm), Type A/E [AP4003705]
Sampling time*

180 min

Sampling volume (TWA)*

180 L

Sampling flow rate (TWA)*

1 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA 1024 (fully validated)
Notes

Samples must be shipped cold overnight and stored in a freezer until analysis.

 

Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA
 

 

TLV-TWA
 

0.05 mg/m³ [1994]

PEL-TWA
 

0.005 mg/m³

PEL-STEL REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

N

Skin notation
 

N

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Tris(2, 3-Epoxypropyl)isocyanurate

NIOSH: Pocket Guide to Chemical Hazards - Not listed

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 1,3,5-Triglycidyl-s-triazinetrione. 2017.
  • Allmaras, S.: Worker exposure to 1,3,5-tryglycidyl isocyanurate (TGIC) in powder paint coating operations. Appl. Occup. Environ. Hyg. 18(3): 151-153, 2003.
  • Anees W, Moore VC, Croft JS, Robertson AS, Burge PS: Occupational asthma caused by heated triglycidyl isocyanurate. Occup Med (Lond) 61(1):65-7, Jan 2011.
  • Lindell, B. and Montelius, J: Triglycidyl isocyanurate [114 KB PDF, 36 pages]. Arbete och Hälsa 18: 1-30, 2001.
  • Meuleman L, Goossens A, Linders C, Rochette F, Nemery B: Sensitization to triglycidylisocyanurate (TGIC) with cutaneous and respiratory manifestations. Allergy 54(7):752-6, July 1999.
  • Piirilä P, Estlander T, Keskinen H, Jolanki R, Laakkonen A, Pfäffli P, Tupasela O, Tuppurainen M, Nordman H.Occupational asthma caused by triglycidyl isocyanurate (TGIC). Clin Exp Allergy 27(5):510-4, May 1997.
  • Sastre J, Carnes J, García del Potro M, Manso L, Aguado E, Fernández-Nieto M: Occupational asthma caused by triglycidyl isocyanurate. Int Arch Occup Environ Health. 84(5):547-9, Jun 2011.
  • World Health Organization (WHO): Triglycidyl Isocyanurate. 1998.

Last Updated Date : 12/14/2020