TERT-BUTYL METHYL ETHER (METHYL TERT-BUTYL ETHER)

Chemical Identification
Chemical Identification
CAS # 1634-04-4
Formula

C₅H₁₂O

Synonyms

methyl-t-butyl Ether; methoxy-2-methyl propane; MTBE

Physical Properties
Physical Properties
Physical description A colorless liquid with a distinctive anesthetic-like odor.
Boiling point 131.4°F Molecular weight 88.17
Freezing point/melting point -164.2°F Vapor pressure
Flash point -14°F Vapor density
Specific gravity 0.7405 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.)
Sampling group
Sampler/Sampling media
Sampling time*
Sampling volume (TWA)*
Sampling flow rate (TWA)*
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments
Method reference
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device CMS Chip
Model/Type MTBE, 10-200 ppm range
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA TLV-TWA

50 ppm [1999]

PEL-TWA

40 ppm (144 mg/m³)

PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

NA

Skin notation

NA

Skin notation

N

Skin notation

N

Notes:

Not established

Notes:

Not established

Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: IARC-3, TLV-A3 Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

5 ppm/1000 ppm/5000 ppm

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Methyl tert-butyl ether

NIOSH: Pocket Guide to Chemical Hazards - Methyl tert-butyl ether

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Methyl tert-butyl ether. See annual publication for most recent information.
  • (absorption; metabolism) Draper, A.J., Madan, A. and Parkinson, A.: Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. Arch. Biolchem. Biophys. 341(1): 47-61, 1997.
  • Prah, J.D., Blount, B., Cardinali, F.L., Ashley, D.L., Leavens, T. and Case, M.W.: The development and testing of a dermal exposure system for pharmacokinetic studies of administered and ambient water contaminants. J. Pharmacol. Toxicol. Methods 47(3): 189-195, 2002.
  • (clinical use) Hellstern, A., et al.: Dissolution of gallbladder stones with methyl tert-butyl ether and stone recurrence: a European survey. Dig. Dis. Sci. 43(5): 911-920, 1998.
  • (general reviews) Borak, J., Pastides, H., Van Ert, M., Russi, M. and Herzstein J.: Exposure to MTBE and acute human health effects: a critical literature review. Human and Ecological Risk Assessment 4(1): 177-200, 1998.
  • No Authors. Methyl tert-butyl ether . IARC Monogr. Eval. Carcinog. Risks Hum. 73: 339-383, 1999.

Last Updated Date : 01/12/2021