PHENYL ETHER (VAPOR)†

Chemical Identification
Chemical Identification
CAS # 101-84-8
Formula

C₁₂H₁₀O

Synonyms

diphenyl ether; diphenyl oxide; phenoxy benzene; phenyl oxide

Physical Properties
Physical Properties
Physical description Colorless, crystalline solid or liquid (above 82°F) with a geranium-like odor.
Boiling point 498°F Molecular weight 170.2
Freezing point/melting point 82°F Vapor pressure 0.02 mmHg at 77°F
Flash point 239°F Vapor density
Specific gravity 1.08 Ionization potential 8.09 eV
Lower explosive limit (LEL) 0.7% Upper explosive limit (UEL) 1.5%
NFPA health rating 1 NFPA fire rating 1
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 2047
Sampling group
Sampler/Sampling media XAD-7 tube (100/50 mg) [SKC 226-95]
Sampling time*

100 min

Sampling volume (TWA)*

20 L

Sampling flow rate (TWA)*

0.2 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA PV2022 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

1 ppm (7 mg/m³)

REL-TWA
 

1 ppm (7 mg/m³)

TLV-TWA
 

1 ppm [1979]

PEL-TWA
 

1 ppm (7 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

2 ppm [1979]

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Notes:
 

This OSHA PEL is also applies to phenyl ether-biphenyl mixture vapors. See 29 CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

100 ppm

Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Diphenyl oxide

NIOSH: Pocket Guide to Chemical Hazards - Phenyl ether (vapor)

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 2017.
  • Api, A.M. and Ford, R.A.: Evaluation of the dermal subchronic toxicity of diphenyl ether in the rat. Food Chem. Toxicol. 41(2): 259-264, 2003.
  • Hefner, R.E., Leong, B.K.J., Kociba, R.J. and Gehring, P.J.: Repeated inhalation toxicity of diphenyl oxide in experimental animals. Toxicol. Appl. Pharmacol. 33(1): 78-86, 1975.
  • Law, F.C. and Chakrabarti, S.: Irreversible binding of 14C-diphenyl ether-derived radioactivity to liver microsomes in vitro and tissue proteins in vivo. Drug Chem. Toxicol. 6(3): 285-294, 1983.
  • Law, F.C., Song, Y.Y. and Chakrabarti, S.: Disposition and metabolism of diphenyl ether in rats. Xenobiotics 13(10): 627-633, 1983.
  • Pohanish, R.P. (editor): Diphenyl oxide. Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 979-980.

Last Updated Date : 01/28/2021