1. OSHA Occupational Chemical Database
  2. NITROGEN DIOXIDE
Label abbreviations descriptions

NITROGEN DIOXIDE†

Chemical Identification
Chemical Identification
CAS # 10102-44-0
Formula
 

NO₂
Synonyms
 

diesel exhaust component, dinitrogen tetroxide (N₂O₄), NO₂, nitrogen peroxide, nitrogen tetroxide
Physical Properties
Physical Properties
Physical description Yellowish-brown liquid or reddish-brown gas (above 70°F) with a pungent, acrid odor.
Boiling point 70°F Molecular weight 46
Freezing point/melting point 15°F Vapor pressure 720 mmHg
Flash point Vapor density 2.62
Specific gravity 1.44 (liquid at 68°F) Ionization potential 9.75 eV
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 3 NFPA fire rating 0
NFPA reactivity rating 0 NFPA special instruction OX: Possesses oxidizing properties
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1903
Sampling group
Sampler/Sampling media 2-section tube packed with a 400 mg TEA-IMS front and a 200 mg back-up section [SKC 226-40-02]
Sampling time*
 

15 min
Sampling volume (TWA)*
 

 
Sampling flow rate (TWA)*
 

 
Sampling volume (STEL/Peak/C)*

3 L

 

 
Sampling flow rate (STEL/Peak/C)*
 

0.2 L/min
Analytical method instruments IC
Method reference OSHA ID-182 (fully validated)
Notes
 

Submit as a separate sample.
Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 
Bulk Method
Bulk Method
 

 
On-Site Screening Techniques
On-Site Screening Techniques
Device CMS Chip
Model/Type Nitrogen dioxide, 0.5-25 ppm range
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

 REL-TWA
 

 

 TLV-TWA
 

0.2 ppm [2011]

 PEL-TWA
 

 
PEL-STEL
 

 

 REL-STEL
 

1 ppm (1.8 mg/m³)

 TLV-STEL
 

 

 PEL-STEL
 

1 ppm (1.8 mg/m³)
PEL-C
 

5 ppm (9 mg/m³)

 REL-C
 

 

 TLV-C
 

 

 PEL-C
 

 
Skin notation
 

N

 Skin notation
 

N

 Skin notation
 

N

 Skin notation
 

N
Notes:
 

See 29 CFR 1910.1000 Table Z-1.

 Notes:
 

 

 Notes:
 

 

 Notes:
 

 
Health factors:  See NIH-NLM PubChem. IDLH
 

20 ppm
Carcinogenic classifications: TLV-A4 Notes:
 

 
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

1 ppm/15 ppm/30 ppm
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Nitrogen dioxide

NIOSH: Pocket Guide to Chemical Hazards - Nitrogen Dioxide

Literature References

 
  • ACGIH: Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Nitrogen Dioxide. See annual publication for most recent information.
  • Douglas, W.W., Hepper, N.G., and Colby, T.V.: Silo-filler's disease. Mayo Clin. Proc. 64(3): 291-304, 1989.
  • Frampton, M.W., Boscia, J., Roberts, N.J. Jr., Azadniv, M., Torres, A., Cox, C., Morrow, P.E., Nichols, J., Chalupa, D., Frasier, L.M., Gibb, F.R., Speers, D.M., Tsai, Y., Utell, M.J.: Nitrogen dioxide exposure: effects on airway and blood cells. Am J Physiol Lung Cell Mol Physiol. 282(1):L155-65, Jan 2002.
  • Helleday, R., Huberman, D., Blomberg, A., Stjernberg, N., Sandstrom, T.: Nitrogen dioxide exposure impairs the frequency of the mucociliary activity. Eur Respir J. 8(10):1664-8, Oct 1995.
  • Linaker, C.H., Coggon, D., Holgate, S.T., Clough, J., Josephs, L., Chauhan, A.J., Inskip, H.M.: Personal exposure to nitrogen dioxide and risk of airflow obstruction in asthmatic children with upper respiratory infection. Thorax. 55(11):930-3, Nov 2000.
  • NIOSH: Criteria for a Recommended Standard - Occupational Exposure to Oxides of Nitrogen (Nitrogen Dioxide and Nitric Oxide). 1976.
  • NIOSH: Occupational Health Guideline for Nitrogen Dioxide. 1978.
  • Pathmanathan, S., Krishna, M.T., Blomberg, A., Helleday, R., Kelly, F.J., Sandstrom, T., Holgate, S.T., Wilson, S.J., Frew, A.J.: Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways. Occup Environ Med. 60(11):892-6, Nov 2003.
  • Roger, L.J., Horstman, D.H., McDonnell, W., Kehrl, H., Ives, P.J., Seal, E., Chapman, R., Massaro, E.: Pulmonary function, airway responsiveness, and respiratory symptoms in asthmatics following exercise in NO2. Toxicol Ind Health. 6(1):155-71, Jan 1990.

Last Updated Date : 01/05/2021