NITRIC OXIDE†

Chemical Identification
Chemical Identification
CAS # 10102-43-9
Formula
 

NO

Synonyms
 

mononitrogen monoxide; nitrogen monoxide

Physical Properties
Physical Properties
Physical description Colorless gas.
Boiling point -241°F Molecular weight 30.01
Freezing point/melting point -263°F Vapor pressure 34.2 atm
Flash point Vapor density 1.04
Specific gravity 1.27 at -238.36° Ionization potential 9.27 eV
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 3 NFPA fire rating 0
NFPA reactivity rating 0 NFPA special instruction OX: Possesses oxidizing properties
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1890
Sampling group
Sampler/Sampling media Sorbent tubes, 2 molecular sieve (triethanolamine) tubes and 1 oxidizer tube [SKC 226-40A]
Sampling time*
 

240 min

Sampling volume (TWA)*
 

6 L

Sampling flow rate (TWA)*
 

0.025 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments IC
Method reference OSHA ID-190 (fully validated)
Notes
 

Submit as separate sample. Only the back tube can be analyzed for NO. The front is analyzed for NO2 by request.

Carefully label tubes before shipping to the SLTC. Do not submit oxidizer tube to the SLTC.

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

25 ppm (30 mg/m³)

REL-TWA
 

25 ppm (30 mg/m³)

TLV-TWA
 

25 ppm [1992]

PEL-TWA
 

25 ppm (30 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

BEI®

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

100 ppm

Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Nitric oxide

NIOSH: Pocket Guide to Chemical Hazards - Nitric oxide

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Nitric oxide. See annual publication for most recent information.
  • Barbinova, L. and Baur, X.: Increase in exhaled nitric oxide (eNO) after work-related isocyanate exposure. Int. Arch. Occup. Environ. Health 79(5): 387-395, 2006.
  • Baur, X. and Barbinova, L.: Latex allergen exposure increases exhaled nitric oxide in symptomatic healthcare workers. Eur. Respir. J. 25(2): 309-316, 2005.
  • Clark, R.H., et al.: Low-dose nitric oxide therapy for persistent pulmonary hypertension of the newborn. N. Engl. J. Med. 342(7): 469-474, 2000.
  • Griffiths, M.J.D. and Evans, T.W.: Inhaled nitric oxide therapy in adults. N. Engl. J. Med. 353(25): 2683-2695, 2005.
  • Maniscalco, M., Grieco, L., Galdi, A., Lundberg, J.O. and Sofia, M.: Increase in exhaled nitric oxide in shoe and leather workers at the end of the work-shift. Occup. Med. (Lond.) 54(6): 404-407, 2004.
  • Morishita, T., et al.: Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms. Proc. Natl. Acad. Sci. USA 102(30): 10616-10621, 2005.
  • Pohanish, R.P. (editor): Nitrogen Dioxide. Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1691-1694.
  • Zeidler, P.C. and Castranova, V: Role of nitric oxide in pathological responses of the lung to exposure to environmental/occupational agents. Redox. Rep. 9(1): 7-18, 2004.

Last Updated Date : 01/28/2021