DI-SEC OCTYL PHTHALATE (DI(2-ETHYLHEXYL) PHTHALATE)†

Chemical Identification
Chemical Identification
CAS # 117-81-7
Formula

C₂₄H₃₈O₄

Synonyms

DEHP; di(2-ethylhexyl)phthalate; DOP; bis-(2-ethylhexyl)phthalate; octyl phthalate;phthalic acid

Physical Properties
Physical Properties
Physical description Colorless, oily liquid with a slight odor.
Boiling point 727°F Molecular weight 390.5
Freezing point/melting point -58°F Vapor pressure 1.32 mmHg at 392°F
Flash point 420°F (open cup) Vapor density 13.45
Specific gravity 0.99 Ionization potential
Lower explosive limit (LEL) 0.3% at 474°F Upper explosive limit (UEL) 0.28% at 507°F
NFPA health rating 0 NFPA fire rating 1
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1015
Sampling group
Sampler/Sampling media OSHA versatile sampler (OVS-Tenax®) - 13 mm Tenax® tube (140/70 mg) with GFF enclosed [SKC 226-56]
Sampling time*
Sampling volume (TWA)*

240 L

Sampling flow rate (TWA)*

1 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA 104 (fully validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

5 mg/m³

REL-TWA

5 mg/m³

TLV-TWA

5 mg/m³ [1996]

PEL-TWA

5 mg/m³

PEL-STEL REL-STEL

10 mg/m³

TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes:

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 0.15 mg/m³). See Appendix A, NIOSH Potential Occupational Carcinogens.

Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

5000 mg/m³

Carcinogenic classifications: IARC-3, NIOSH-Ca, NTP-R, TLV-A3, EPA-B2 Notes:

Ca

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Di(2-ethylhexyl) phthalate

NIOSH: Pocket Guide to Chemical Hazards - Di-sec octyl phthalate

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Di(2-ethylhexyl) phthalate. See annual publication for most recent information.
  • EPA Air Toxics Website: Bis(2-ethylhexyl) phthalate (DEHP). U.S. Environmental Protection Agency Technology Transfer Network.
  • Foster, P.M.D., Mylchreest, E., Guido, K.W. and Sar, M.: Effects of phthalate esters on the developing reproductive tract of male rats. Human Reprod. Update 7(3): 231-235, 2001.
  • Koch, H.M., Bolt, H.M., Preuss, R. and Angerer, J.: New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP. Arch. Toxicol. 79(7): 367-376, 2005.
  • Lovekamp-Swan, T. and Davis, B.J.: Mechanisms of phthalate ester toxicity in the female reproductive system. Environ. Health Perspect. 111(2): 139-145, 2003.
  • Pohanish, R.P. (editor): Di(2-Ethylhexyl)phthalate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 873-876.
  • Shea, K.M. and American Academy of Pediatrics Committee on Environmental Health. Pediatric exposure and potential toxicity of phthalate plasticizers. Pediatrics 111(6 Pt. 1): 1467-1474, 2003.
  • Tickner, J.A., Schettler, T., Guidotti, T., McCally, M. and Rossi, M.: Health risks posed by use of di-2-ethyhexyl phthalate (DEHP) in PVC medical devices: a critical review. Am. J. Ind. Med. 39(1): 100-111, 2001.

Last Updated Date : 12/28/2020