GLUTARALDEHYDE

Chemical Identification
Chemical Identification
CAS # 111-30-8
Formula

C₅H₈O₂

Synonyms

glutaric dialdehyde; 1,5-pentanedial

Physical Properties
Physical Properties
Physical description Colorless liquid with a pungent odor.
Boiling point 369-372° Molecular weight 100.1
Freezing point/melting point 7°F Vapor pressure 17 mmHg
Flash point Vapor density
Specific gravity 1.10 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1361
Sampling group
Sampler/Sampling media 2 GFFs (open-faced) in 1 cassette separated by a spacer. GFFs are coated with 2,4-dinitrophenylhydrazine (DNPH) and phosphoric acid. [SKC 225-9019]
Sampling time*

15 min

Sampling volume (TWA)*

15 L

Sampling flow rate (TWA)*

1 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments HPLC-UV
Method reference OSHA 64 (fully validated)
Notes
 

Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible.

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

 

TLV-TWA
 

 

PEL-TWA
 

 

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

0.2 ppm (0.8 mg/m³)

TLV-C
 

0.05 ppm [1998]

PEL-C
 

0.05 ppm (0.2 mg/m³)

Skin notation
 

NA

Skin notation
 

Y

Skin notation
 

Y

Skin notation
 

N

Notes:
 

Not established

Notes:
 

See Appendix C, Supplementary Exposure Limits (Aldehydes).

Notes:
 

dermal sensitizer (DSEN), respiratory sensitizer (RSEN)

Notes:
 

See footnote [t].

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: TLV-A4 Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

0.2 ppm/1 ppm/5 ppm

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Glutaraldehyde solution

NIOSH: Pocket Guide to Chemical Hazards - Glutaraldehyde

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Glutaraldehyde [111-30-8], activated or unactivated. See annual publication for most recent information.
  • California Occupational Safety & Health Standards Board: Initial and Final Statement of Reasons. July 6, 2006.
  • NIOSH: Skin Notation Profiles - Glutaraldehyde. April 2011.
  • NIOSH: Recommendations for Occupational Safety and Health - Compendium of Policy Documents and Statements. Cincinnati, OH: U.S. Department of Health and Human Services (DHHS). NIOSH Publication No. 92-100. (1992).
  • Shaffer, M.P. and Delsito, D.V.: Allergic contact dermatitis from glutaraldehyde in health-care workers. Contact Dermatitis 43(3): 150-156, 2000.
  • Zeiger E, Gollapudi B, Spencer P: Genetic toxicity and carcinogenicity studies of glutaraldehyde—a review. Mutat Res. 589(2):136-51. March 2005.

Last Updated Date : 12/29/2020