N-NITROSODIBUTYLAMINE

Chemical Identification
Chemical Identification
CAS # 924-16-3
Formula

C₈H₁₈N₂O

Synonyms

butylamine, N-nitrosodi; N-butyl-N-nitroso-1-butamine; DBN; DBNA; dibutylamine, N-nitroso; dibutylnitrosamine; di-n-butylnitrosamine; N,N-di-n-butylnitrosamine; NDBA; N-nitroso-di-n-butylamine

Physical Properties
Physical Properties
Physical description Pale yellow liquid.
Boiling point 116°C at 14 mmHg Molecular weight 158.25
Freezing point/melting point Vapor pressure
Flash point Vapor density 0.9009
Specific gravity Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1944
Sampling group
Sampler/Sampling media ThermoSorb/N air sampler [No longer available]
Sampling time*

75 min

Sampling volume (TWA)*

75 L

Sampling flow rate (TWA)*

1 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-TEA
Method reference OSHA 27 (fully validated)
Notes

 †This media is no longer available. OSHA staff please contact the SLTC prior to sampling at (801) 233-4900.

Special requirements

Store samples in freezer.

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA
 

 

TLV-TWA
 

 

PEL-TWA
 

 

PEL-STEL REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

NA

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

Not established

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: NTP, IARC-2B, EPA-B2 Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - N-Nitrosodi-n-butylamine

NIOSH: Pocket Guide to Chemical Hazards - N-Nitrosodi-n-butylamine

Literature References

 
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: EJ4025000.
  • U.S. EPA Integrated Risk Information System: N-Nitroso-di-n-butylamine (CASRN 924-16-3).
  • No Author: N-Nitrosodi-n-Butylamine, CAS No. 924-16-3. Report on Carcinogens (latest edition); U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program, 2005.
  • Bellec, G., Dréano, Y., Bail, J.-P., Ménez, J.-F. and Berthou, F.: Cytochrome P450 hydroxylation of carbon atoms of the alkyl chain of symmetrical N-nitrosodialkylamines by human liver microsomes. Mutat. Res. 377(2): 199-209, 1997.
  • Dallinga, J.W., et al.: Volatile N-nitrosamines in gastric juice of patients with various conditions of the gastrointestinal tract determined by gas chromatography-mass spectrometry and related to intragastric pH and nitrate and nitrite levels. Cancer Lett. 124(2): 119-125, 1998.
  • Fiddler, W., Pensabene, J., Sphon, J. and Andrzejewski. D.: Nitrosamines in rubber bands used for orthodontic purposes. Food Chem. Toxicol. 30(4): 325-326, 1992.
  • Heenan, M.P., Nacey, J.N., Delahunt, B., Ferguson, A.F. and Dickson, S.J.: Volatile N-nitrosamines in urinary catheters. Br. J. Urol. 63(1): 72-75, 1989.
  • Pohanish, R.P. (editor): N-Nitrosodi-n-Butylamine. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1728-1730.

Last Updated Date : 01/05/2021