2-AMINO-2-METHYLPROPANOL

Chemical Identification
Chemical Identification
CAS # 124-68-5
Formula

C₄H₁₁NO

Synonyms

AMP; 2-aminodimethylethanol; β -aminoisobutanol; 2-amino-2-methylpropan-1-ol; 2-amino-2-methyl-1-propanol; isobutanol-2-amine; isobutanolamine

Physical Properties
Physical Properties
Physical description A clear light colored liquid.
Boiling point 329°F Molecular weight 89.14
Freezing point/melting point 89.6°F Vapor pressure
Flash point 153°F Vapor density
Specific gravity 0.935 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 2 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) A615
Sampling group
Sampler/Sampling media XAD-2 tube (80/40) coated with 10% 1-naphthylisothiocyanate (NITC) [SKC 226-30-18]
Sampling time*

100 min

Sampling volume (TWA)*

10 L

Sampling flow rate (TWA)*

0.1 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments LC-UV
Method reference OSHA PV2145 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

 

TLV-TWA
 

 

PEL-TWA
 

 

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

NA

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

Not established

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - 2-Amino-2-methyl-1-propanol

NIOSH: Pocket Guide to Chemical Hazards - Not listed

Literature References

 
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: UA5950000
  • Cipolla, C., et al.: Airborne contact dermatitis from 2-amino-2-methyl-1-propanol in a cosmetic company. Arh. Hig. Rada Toksikol. 48(2): 205-209, 1997.
  • Cosmetic Ingredient Review Board: A final report on the safety assessment of aminomethylpropanol and aminomethylpropanediol. J. Am. Coll. Toxicol. 9(2): 203-228, 1990.
  • Detwiler-Okabayashi, K.A. and Schaper, M.M.: Respiratory effects of a synthetic metalworking fluid and its components. Arch. Toxicol. 70(3-4): 195-201, 1996.
  • Yue, K.T., Mulford, D.J. and Russell, P.J.: The metabolism of 2-amino-2-methylpropanol in young rats. Arch. Biochem. Biophys. 136(1): 47-53, 1970.

Last Updated Date : 12/15/2020