1-AMINO-2-PROPANOL

Chemical Identification
Chemical Identification
CAS # 78-96-6
Formula
 

C₃H₉NO

Synonyms
 

1-aminopropan-2-ol; ⍺-aminoisopropyl alcohol; 2-hydroxypropylamine; isopropanolamine; 1-methyl-2-aminoethanol

Physical Properties
Physical Properties
Physical description A colorless liquid with a slight ammonia-like odor.
Boiling point 313-316°F Molecular weight 75.13
Freezing point/melting point 34.5°F Vapor pressure 2.59 mmHg
Flash point 171°F Vapor density 2.6
Specific gravity 0.961 Ionization potential
Lower explosive limit (LEL) 2.20% Upper explosive limit (UEL) 12%
NFPA health rating 3 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) A606
Sampling group
Sampler/Sampling media XAD-2 tube (80/40) coated with 10% 1-naphthylisothiocyanate (NITC) [SKC 226-30-18]
Sampling time*
 

200 min

Sampling volume (TWA)*
 

20 L

Sampling flow rate (TWA)*
 

0.1 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments HPLC
Method reference OSHA PV2122 (partially validated)
Notes
 

 

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

 

TLV-TWA
 

 

PEL-TWA
 

 

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

NA

Skin notation
 

NA

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

Not established

Notes:
 

Not established

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Monoisopropanolamine

NIOSH: Pocket Guide to Chemical Hazards - Not listed

Literature References

 
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: UA5775000
  • International Chemical Safety Cards (WHO/IPCS/ILO): Isopropanolamine.
  • Detwiler-Okabayashi, K.A. and Schaper, M.M.: Respiratory effects of a synthetic metalworking fluid and its components. Arch. Toxicol. 70(3-4): 195-201, 1996.
  • Geier, J., et al.: Patch testing with components of water-based metalworking fluids: results of a multicentre study with a second series. Contact Dermatitis 55(6): 322-329, 2006.
  • Hervin, R.L. and Lucas, J.B.: Occupational Health Case Report No. 8. Monoisopropanolamine. J. Occup. Med. 16(5): 355-357, 1974.
  • No authors listed: Summary of Evaluations Performed by the Joint FAO/WHO Expert Committee on Food Additives, 1-Amino-2-propanol.

Last Updated Date : 12/15/2020