1-METHOXY-2-PROPANOL

Chemical Identification
Chemical Identification
CAS # 107-98-2
Formula

C₄H₁₀O₂

Synonyms

Dowtherm209®; 1-methoxy-2-hydroxypropane; 1-methoxy-2-propanol; 2-methoxy-1-methylethanol; propylene glycol methyl ether

Physical Properties
Physical Properties
Physical description Clear, colorless liquid with a mild, ethereal odor.
Boiling point 248°F Molecular weight 90.1
Freezing point/melting point -139°F (sets to glass) Vapor pressure 12 mmHg
Flash point 97°F Vapor density 3.11
Specific gravity 0.96 Ionization potential
Lower explosive limit (LEL) 1.6% Upper explosive limit (UEL) 13.8%
NFPA health rating 1 NFPA fire rating 3
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 2210
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*

100 min

Sampling volume (TWA)*

10 L

Sampling flow rate (TWA)*

0.1 L/min

Sampling volume (STEL/Peak/C)*

3 L

Sampling flow rate (STEL/Peak/C)*

0.2 L/min

Analytical method instruments GC-FID
Method reference OSHA 99 (fully validated)
Notes
 

Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible.

Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA

100 ppm (360 mg/m³)

TLV-TWA

50 ppm [2012]

PEL-TWA

100 ppm (360 mg/m³)

PEL-STEL REL-STEL

150 ppm (540 mg/m³)

TLV-STEL

100 ppm [2012]

PEL-STEL

150 ppm (540 mg/m³)

PEL-C REL-C TLV-C PEL-C
Skin notation

NA

Skin notation

N

Skin notation

N

Skin notation

Y

Notes:

Not established

Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: TLV-A4 Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - 1-Methoxy-2-propanol

NIOSH: Pocket Guide to Chemical Hazards - Propylene glycol monomethyl ether

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 1-Methoxy-2-propanol. See annual publication for most recent information.
  • EPA Integrated Risk Information System: Propylene glycol monomethyl ether (PGME) (CASRN 107-98-2).
  • Devanthéry, A., Berode, M. and Droz, P.O.: Propylene glycol monomethyl ether occupational exposure. 3. Exposure of human volunteers. Int. Arch. Occup. Environ. Health 75(4): 203-208, 2002.
  • Emmen, H.H., Muijser, H., Arts, J.H. and Prinsen, M.K.: Human volunteer study with PGME: eye irritation during vapor exposure. Toxicol. Lett. 140-141: 249-259, 2003.
  • Pohanish, R.P. (editor): Propylene Glycol Monomethyl Ether. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1974-1976.
  • Wilkinson, S.C. and Williams, F.M.: Effects of experimental conditions on absorption of glycol ethers through human skin in vitro. Int. Arch. Occup. Environ. Health 75(8): 519-527, 2002.

Last Updated Date : 12/15/2020