HEXAMETHYLENE DIISOCYANATE

Chemical Identification
Chemical Identification
CAS # 822-06-0, 11142-52-2
Formula

C₈H₁₂N₂O₂

Synonyms

1,6-diisocyanatohexane, HDI, hexamethylene-1,6-diisocyanate, 1,6-hexamethylene diisocyanate

Physical Properties
Physical Properties
Physical description Clear, colorless to slightly yellow liquid with a sharp, pungent odor.
Boiling point 415°F Molecular weight 168.2
Freezing point/melting point -89°F Vapor pressure 0.5 mmHg
Flash point 284°F Vapor density
Specific gravity 1.0528 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1377
Sampling group
Sampler/Sampling media Isocyanate Sampling Filter Kit - GFF (37 mm, open-faced) coated with 1 mg 1-(2-pyridyl)piperazine [SLTC103]
Sampling time*

15 min

Sampling volume (TWA)*
 

15 L

Sampling flow rate (TWA)*
 

1 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments LC
Method reference OSHA 5002 (fully validated)
Notes
 

Results may not reflect accurate exposures to the polymeric forms of isocyanates. Refrigerate coated filters until used. Sample open-faced!!

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

0.005 ppm (0.035 mg/m³)

TLV-TWA
 

0.005 ppm [1985]

PEL-TWA
 

0.005 ppm (0.034 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

0.020 ppm (0.140 mg/m³) [10 minutes]

TLV-C
 

 

PEL-C
 

 

Skin notation
 

NA

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Notes:
 

Not established

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Hexamethylene diisocyanate

NIOSH: Pocket Guide to Chemical Hazards - Hexamethylene diisocyanate

Literature References

 

Last Updated Date : 04/14/2021