1. OSHA Occupational Chemical Database
  2. ETHYLENEDIAMINE (1,2-DIAMINOETHANE)
Label abbreviations descriptions

ETHYLENEDIAMINE (1,2-DIAMINOETHANE)†

Chemical Identification
Chemical Identification
CAS # 107-15-3
Formula

C₂H₈N₂
Synonyms

1,2-diaminoethane; 1,2-ethanediamine; ethylenediamine (anhydrous)
Physical Properties
Physical Properties
Physical description Colorless, viscous liquid with an ammonia-like odor.
Boiling point 241°F Molecular weight 60.1
Freezing point/melting point 47°F Vapor pressure 11 mmHg
Flash point 93°F Vapor density 2.07
Specific gravity 0.91 Ionization potential 8.60 eV
Lower explosive limit (LEL) 4.2% Upper explosive limit (UEL) 14.4%
NFPA health rating 3 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction 0
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1130
Sampling group
Sampler/Sampling media XAD-2 tube (80/40) coated with 10% 1-naphthylisothiocyanate (NITC) [SKC 226-30-18]
Sampling time*

100 min
Sampling volume (TWA)*

10 L
Sampling flow rate (TWA)*

0.1 L/min
Sampling volume (STEL/Peak/C)*
 

 
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments HPLC
Method reference OSHA 60 (fully validated)
Notes
 

 
Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 
Bulk Method
Bulk Method
 

 
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

10 ppm (25 mg/m³)

 REL-TWA
 

10 ppm (25 mg/m³)

 TLV-TWA
 

10 ppm [1990]

 PEL-TWA
 

10 ppm (25 mg/m³)
PEL-STEL
 

 

 REL-STEL
 

 

 TLV-STEL
 

 

 PEL-STEL
 

 
PEL-C
 

 

 REL-C
 

 

 TLV-C
 

 

 PEL-C
 

 
Skin notation
 

N

 Skin notation
 

N

 Skin notation
 

Y

 Skin notation
 

N
Notes:
 

See 29 CFR 1910.1000 Table Z-1.

 Notes:
 

 

 Notes:
 

 

 Notes:
 

 
Health factors:  See NIH-NLM PubChem. IDLH
 

1000 ppm
Carcinogenic classifications: TLV-A4, EPA-D Notes:
 

 
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Ethylenediamine

NIOSH: Pocket Guide to Chemical Hazards - Ethylenediamine

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Ethylenediamine. See annual publication for most recent information.
  • EPA Integrated Risk Information System: Ethylene diamine (CASRN 107-15-3).
  • Leung, H.-W.: Pharmacokinetics and metabolism of ethylenediamine in the Swiss Webster mouse following oral or intravenous dosing. Toxicol. Lett. 117(1-2): 107-114, 2000.
  • Pohanish, R.P. (editor): Ethylenediamine. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1079-1081.
  • Sasseville, D. and al-Khenaisan, S.: Occupational contact dermatitis from ethylenediamine in a wire-drawing lubricant. Contact Dermatitis 36(4): 228-229, 1997.

Last Updated Date : 12/28/2020