HEXAMETHYL PHOSPHORAMIDE
| Chemical Identification | |
|---|---|
| CAS # | 680-31-9 |
| Formula |
C₆H₁₈N₃OP |
| Synonyms |
hexamethylphosphoric acid triamide; hexamethylphosphorotriamide; HMPA; tris(dimethylamino)phosphine oxide; HEMPA; HMPT |
| Physical Properties | |||
|---|---|---|---|
| Physical description | Clear, colorless to light amber liquid with an aromatic or mild, amine-like odor. | ||
| Boiling point | 451°F | Molecular weight | 179.2 |
| Freezing point/melting point | 43°F | Vapor pressure | 0.03 mmHg |
| Flash point | 220°F | Vapor density | 6.18 |
| Specific gravity | 1.024 | Ionization potential | |
| Lower explosive limit (LEL) | Upper explosive limit (UEL) | ||
| NFPA health rating | NFPA fire rating | ||
| NFPA reactivity rating | NFPA special instruction | ||
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Monitoring Methods Used by OSHA | ||||||
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| Analyte code (IMIS no.) | ||||||
| Sampling group | ||||||
| Sampler/Sampling media | ||||||
| Sampling time* | ||||||
| Sampling volume (TWA)* | ||||||
| Sampling flow rate (TWA)* |
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| Sampling volume (STEL/Peak/C)* |
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| Sampling flow rate (STEL/Peak/C)* |
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| Analytical method instruments | ||||||
| Method reference | ||||||
| Notes |
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| Special requirements |
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* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Method | |
|---|---|
| Sampler/Sampling media |
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| Bulk Method |
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| On-Site Screening Techniques | ||||||
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| Device | ||||||
| Model/Type | ||||||
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Sampling information (see manufacturer instructions) |
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| Exposure Limits | |||||||
|---|---|---|---|---|---|---|---|
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
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| PEL-TWA |
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REL-TWA |
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TLV-TWA |
No TLV value [1990] |
PEL-TWA |
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| PEL-STEL |
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REL-STEL |
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TLV-STEL |
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PEL-STEL |
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| PEL-C |
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REL-C |
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TLV-C |
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PEL-C |
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| Skin notation |
NA |
Skin notation |
N |
Skin notation |
Y |
Skin notation |
NA |
|
Notes:
Not established |
Notes:
CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A, NIOSH Potential Occupational Carcinogens. |
Notes:
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Notes:
Not established |
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| Health factors: See NIH-NLM PubChem. | IDLH | ||||||
| Carcinogenic classifications: NTP-R,IARC-2B, NIOSH-Ca, TLV-A3 |
Notes:
Ca |
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AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
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| Additional Resources and Literature References |
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NOAA: CAMEO Chemicals - Hexamethylphosphoramide NIOSH: Pocket Guide to Chemical Hazards - Hexamethyl phosphoramide Literature References
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Last Updated Date : 01/28/2021