Label abbreviations descriptions

HEXAMETHYL PHOSPHORAMIDE

Chemical Identification
CAS # 680-31-9
Formula

C₆H₁₈N₃OP
Synonyms

hexamethylphosphoric acid triamide; hexamethylphosphorotriamide; HMPA; tris(dimethylamino)phosphine oxide; HEMPA; HMPT

Physical Properties
Physical description Clear, colorless to light amber liquid with an aromatic or mild, amine-like odor.
Boiling point 451°F Molecular weight 179.2
Freezing point/melting point 43°F Vapor pressure 0.03 mmHg
Flash point 220°F Vapor density 6.18
Specific gravity 1.024 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)
Sampling group
Sampler/Sampling media
Sampling time*
Sampling volume (TWA)*
Sampling flow rate (TWA)*
 

 
Sampling volume (STEL/Peak/C)*
 

 
Sampling flow rate (STEL/Peak/C)*
 

 
Analytical method instruments
Method reference
Notes
 

 
Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
 

 
Bulk Method
 

 

On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)

Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

 REL-TWA
 

 

 TLV-TWA
 

No TLV value [1990]

 PEL-TWA
 

 
PEL-STEL
 

 

 REL-STEL
 

 

 TLV-STEL
 

 

 PEL-STEL
 

 
PEL-C
 

 

 REL-C
 

 

 TLV-C
 

 

 PEL-C
 

 
Skin notation
 

NA

 Skin notation
 

N

 Skin notation
 

Y

 Skin notation
 

NA
Notes:
 

Not established

 Notes:
 

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A, NIOSH Potential Occupational Carcinogens.

 Notes:
 

 

 Notes:
 

Not established
Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: NTP-R,IARC-2B, NIOSH-Ca, TLV-A3 Notes:
 

Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References

Last Updated Date : 01/28/2021