ISOPROPYL ALCOHOL (2-PROPANOL)†

Chemical Identification
Chemical Identification
CAS # 67-63-0
Formula

C₃H₈O

Synonyms

dimethyl carbinol, IPA, isopropanol, sec-propyl alcohol, rubbing alcohol, isopropyl alcohol

Physical Properties
Physical Properties
Physical description Colorless liquid with the odor of rubbing alcohol.
Boiling point 181°F Molecular weight 60.1
Freezing point/melting point -127°F Vapor pressure 33 mmHg
Flash point 53°F Vapor density 2.07
Specific gravity 0.79 Ionization potential 10.10 eV
Lower explosive limit (LEL) 2.0% Upper explosive limit (UEL) 12.7% at 200°F
NFPA health rating 1 NFPA fire rating 3
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1560
Sampling group OVSG-2
Sampler/Sampling media 2 Anasorb 747 sampling tubes (6 mm glass tubes, the front tube contains 400 and the back 200 mg of sorbent) connected in series [SKC 226-82]
Sampling time*

240 min

Sampling volume (TWA)*

12 L

Sampling flow rate (TWA)*

0.05 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA 5001 (fully validated)
Notes

Separate tubes and seal each after sampling.

Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device Detector tube Detector tube Detector Tube Detector Tube
Model/Type Gastec 113 Gastec 113L Matheson-Kitagawa 8014-122SA Matheson-Kitagawa 8014-150U
Sampling information
(see manufacturer instructions)
0.5 to 2 strokes, 0.004% - 5% range, uncertainty 25% for 50-200 ppm, 16% for 200-800 ppm 1 or 2 strokes, 5-800 ppm range, uncertainty 25% for 50-200 ppm, 16% for 200-800 ppm 1 stroke, 0.02-2.5% range 1 or 2 strokes, approx 10-1200 ppm range
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

400 ppm (980 mg/m³)

REL-TWA

400 ppm (980 mg/m³)

TLV-TWA

200 ppm [2001]

PEL-TWA

400 ppm (980 mg/m³)

PEL-STEL REL-STEL

500 ppm (1225 mg/m³)

TLV-STEL

400 ppm [2001]

PEL-STEL

500 ppm (1225 mg/m³)

PEL-C REL-C TLV-C PEL-C
Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes: Notes:

BEI®

Notes:
Health factors:  See NIH-NLM PubChem. IDLH

2000 ppm

Carcinogenic classifications: IARC-3, TLV-A4 Notes:

10% of LEL

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Isopropanol

NIOSH: Pocket Guide to Chemical Hazards - Isopropanol alcohol

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Isopropanol. See annual publication for most recent information.
  • Ernstgård, L., Sjögren, B., Warholm, M. and Johanson, G.: Sex differences in the toxicokinetics of inhaled solvent vapors in humans. 2. 2-propanol. Toxicol. Appl. Pharmacol. 193(2): 158-167, 2003.
  • Garcia-Gavin, J., Lissens, R., Timmermans, A., Goossens, A.: Allergic contact dermatitis caused by isopropyl alcohol: a missed allergen?. Contact Dermatitis. 65(2):101-106, 2011.
  • NIOSH: Criteria for a Recommended Standard - Occupational Exposure to Isopropyl Alcohol. March 1976.
  • NIOSH: Occupational Health Guideline for Isopropyl Alcohol. September 1978.

Last Updated Date : 12/31/2020