METHYL ISOCYANATE†
Chemical Identification | |
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CAS # | 624-83-9 |
Formula |
C₂H₃NO |
Synonyms |
methyl ester of isocyanic acid; MIC; isocyanatomethane |
Physical Properties | |||
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Physical description | Colorless liquid with a sharp, pungent odor. | ||
Boiling point | 102°F | Molecular weight | 57.05 |
Freezing point/melting point | -112°F | Vapor pressure | 348 mmHg |
Flash point | 19°F | Vapor density | |
Specific gravity | 0.96 | Ionization potential | 10.67 eV |
Lower explosive limit (LEL) | 5.3% | Upper explosive limit (UEL) | 26% |
NFPA health rating | 4 | NFPA fire rating | 3 |
NFPA reactivity rating | 2 | NFPA special instruction | W: Reacts violently or explosively with water. |
Vapor hazard ratio (VHR) | |||
Historical exceedance percentage | |||
Target organs |
Monitoring Methods Used by OSHA | ||||||
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Analyte code (IMIS no.) | 1773 | |||||
Sampling group | ||||||
Sampler/Sampling media | XAD-7 tube coated with 0.3 mg of 1-(2-pyridyl)piperazine (1-2PP) [No longer available] | |||||
Sampling time* | 300 min |
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Sampling volume (TWA)* | 15 L |
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Sampling flow rate (TWA)* | 0.05 L/min |
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Sampling volume (STEL/Peak/C)* |
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Sampling flow rate (STEL/Peak/C)* |
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Analytical method instruments | HPLC | |||||
Method reference | OSHA 54 (fully validated) | |||||
Notes | This media is no longer available. OSHA staff please contact the SLTC prior to sampling at (801) 233-4900. |
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Special requirements |
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* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
Wipe Method | |
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Sampler/Sampling media |
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Bulk Method |
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On-Site Screening Techniques | ||||||
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Device | Infrared spectrophotometer | Photoionization Detector (PID) | ||||
Model/Type | Miran 1A & 1B | |||||
Sampling information (see manufacturer instructions) |
0.1 ppm@4.4 µm |
Exposure Limits | |||||||
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OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
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PEL-TWA |
0.02 ppm (0.05 mg/m³) |
REL-TWA |
0.02 ppm (0.05 mg/m³) |
TLV-TWA |
0.02 ppm [2013] |
PEL-TWA |
0.02 ppm (0.05 mg/m³) |
PEL-STEL |
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REL-STEL |
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TLV-STEL |
0.06 ppm [2013] |
PEL-STEL |
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PEL-C |
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REL-C |
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TLV-C |
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PEL-C |
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Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
Notes: |
Notes:
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Notes:
dermal sensitization (DSEN) |
Notes:
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Health factors: See NIH-NLM PubChem. | IDLH |
3 ppm |
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Carcinogenic classifications: Not listed |
Notes:
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AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
0.025 ppm/0.25 ppm/1.5 ppm |
Additional Resources and Literature References |
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NOAA: CAMEO Chemicals - Methyl isocyanate NIOSH: Pocket Guide to Chemical Hazards - Methyl isocyanate Literature References
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Last Updated Date : 01/05/2021