1-CHLORO-1-NITROPROPANE | Occupational Safety and Health Administration

1-CHLORO-1-NITROPROPANE†

Chemical Identification
CAS #	600-25-9
Formula	C₃H₆ClNO₂
Synonyms	Korax; Lanstan

Physical Properties
Physical description	Colorless liquid with an unpleasant odor.
Boiling point	289°F	Molecular weight	123.6
Freezing point/melting point		Vapor pressure	6 mmHg
Flash point	144°F (open cup)	Vapor density	4.26
Specific gravity	1.21	Ionization potential	9.90 eV
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	3	NFPA fire rating	2
NFPA reactivity rating	3	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0660
Sampling group
Sampler/Sampling media	Chromosorb 108® (400/200 mg)
Sampling time^*
Sampling volume (TWA)^*	12 L
Sampling flow rate (TWA)^*	0.2 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	NIOSH S211 (fully validated)
Notes	OSHA staff - please contact the SLTC before sampling at (801) 233-4900.
Special requirements	Chromosorb® 108 resin must be washed with methylene chloride and ethyl acetate before use.

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Sampler/Sampling media

Bulk Method
Bulk Method

On-Site Screening Techniques
Device	Infrared spectrophotometer	Infrared spectrophotometer
Model/Type	Miran 1A & 1B	Miran 103
Sampling information (see manufacturer instructions)	1.6 ppm@12.4 µm	0-100 ppm@12.4 µm

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	20 ppm(100 mg/m³)	REL-TWA	2 ppm (10 mg/m³)	TLV-TWA	2 ppm [1971]	PEL-TWA	2 ppm (10 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH	100 ppm
Carcinogenic classifications: Not listed		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - 1-Chloro-1-nitropropane

NIOSH: Pocket Guide to Chemical Hazards - 1-Chloro-1-nitropropane

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 1-Chloro-1-nitropropane. See annual publication for most recent information.
Occupational Health Guidelines for Chemical Hazards. U.S. Department of Health and Human Services (DHHS), National Institute for Occupational Safety and Health (NIOSH) Publication No. 81-123, (1981, January). Provides a table of contents of guidelines for many hazardous chemicals. The files provide technical chemical information, including chemical and physical properties, health effects, exposure limits, and recommendations for medical monitoring, personal protective equipment (PPE), and control procedures.

Last Updated Date : 12/15/2020