PARATHION†

Chemical Identification
Chemical Identification
CAS # 56-38-2
Formula

C₁₀H₁₄NO₅PS

Synonyms

O,O-diethyl-O(p-nitrophenyl) phosphorothioate; diethyl parathion; ethyl parathion; parathion-ethyl

Physical Properties
Physical Properties
Physical description Pale-yellow to dark-brown liquid with a garlic-like odor.
Boiling point 707°F Molecular weight 291.3
Freezing point/melting point 43°F Vapor pressure 0.00004 mmHg
Flash point 248-320F Vapor density
Specific gravity 1.27 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 4 NFPA fire rating 1
NFPA reactivity rating 2 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1984
Sampling group
Sampler/Sampling media OSHA versatile sampler (OVS-2) - 13 mm XAD-2 tube (270/140 mg) with GFF enclosed [SKC 226-30-16]
Sampling time*

480 min

Sampling volume (TWA)*

480 L

Sampling flow rate (TWA)*

1 L/min

Sampling volume (STEL/Peak/C)*

15 L

Sampling flow rate (STEL/Peak/C)*

1 L/min

Analytical method instruments GC-FPD
Method reference OSHA 62 (fully validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media

Wipe with GFF (37 mm), Type A/E [AP4003705]

Bulk Method
Bulk Method

Limit the amount of bulk submitted to 1 g or 1 mL.

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

0.1 mg/m³

REL-TWA

0.05 mg/m³

TLV-TWA

0.05 mg/m³ (inhalable fraction and vapor) [2000]

PEL-TWA

0.1 mg/m³

PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

Y

Skin notation

Y

Skin notation

Y

Skin notation

Y

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes: Notes:

BEI®

Notes:
Health factors:  See NIH-NLM PubChem. IDLH

10 mg/m³

Carcinogenic classifications: IARC-3, TLV-A4, EPA-C Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Parathion

NIOSH: Pocket Guide to Chemical Hazards - Parathion

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 2017.
  • EPA Air Toxics Website: Parathion. U.S. Environmental Protection Agency Technology Transfer Network.
  • Lee, B.W., London, L., Paulauskis, J., Myers, J. and Christiani, D.C.: Association between human paraoxonase gene polymorphinsm and chronic symptoms in pesticide-exposed workers. J. Occup. Environ. Med. 45(2): 118-122, 2003.
  • Mutch, E., Daly, A.K., Leathart, J.B.S., Blain, P.G. and Williams, F.M.: Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man? Arch. Toxicol. 77(6): 313-320, 2003.
  • Pohanish, R.P. (editor): Parathion. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1788-1791.

Last Updated Date : 01/07/2021